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Literature DB >> 6328429

Nucleotide sequence of two rasH related-genes isolated from the yeast Saccharomyces cerevisiae.

R Dhar, A Nieto, R Koller, D DeFeo-Jones, E M Scolnick.

Abstract

A complete nucleotide sequence of two ras-related yeast genes (c- rassc -1 and c- rassc -2) isolated from the yeast strain Saccharomyces cerevisiae is reported. They encode predicted polypeptides of 40,000 and 41,000 daltons, respectively. The N-terminal 170 amino acids from both genes show extensive amino acid homology to other ras genes from vertebrates, whereas their C-termini have diverged. These genes should be useful in the elucidation of a normal biological function of ras-related genes in a simple system like yeast.

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Year: 1984 PMID： 6328429 PMCID： PMC318772 DOI： 10.1093/nar/12.8.3611

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

16 in total

1. A new method for sequencing DNA.

Authors: A M Maxam; W Gilbert
Journal: Proc Natl Acad Sci U S A Date: 1977-02 Impact factor: 11.205

2. Mechanism of activation of a human oncogene.

Authors: C J Tabin; S M Bradley; C I Bargmann; R A Weinberg; A G Papageorge; E M Scolnick; R Dhar; D R Lowy; E H Chang
Journal: Nature Date: 1982-11-11 Impact factor: 49.962

3. Transcription terminates in yeast distal to a control sequence.

Authors: S Henikoff; J D Kelly; E H Cohen
Journal: Cell Date: 1983-06 Impact factor: 41.582

4. Acquisition of transforming properties by alternative point mutations within c-bas/has human proto-oncogene.

Authors: Y Yuasa; S K Srivastava; C Y Dunn; J S Rhim; E P Reddy; S A Aaronson
Journal: Nature Date: 1983-06-30 Impact factor: 49.962

5. Proposal for naming host cell-derived inserts in retrovirus genomes.

Authors: J M Coffin; H E Varmus; J M Bishop; M Essex; W D Hardy; G S Martin; N E Rosenberg; E M Scolnick; R A Weinberg; P K Vogt
Journal: J Virol Date: 1981-12 Impact factor: 5.103

6. A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene.

Authors: E P Reddy; R K Reynolds; E Santos; M Barbacid
Journal: Nature Date: 1982-11-11 Impact factor: 49.962

7. Saccharomyces cerevisiae synthesizes proteins related to the p21 gene product of ras genes found in mammals.

Authors: A G Papageorge; D Defeo-Jones; P Robinson; G Temeles; E M Scolnick
Journal: Mol Cell Biol Date: 1984-01 Impact factor: 4.272

8. Identification of a precursor in the biosynthesis of the p21 transforming protein of harvey murine sarcoma virus.

Authors: T Y Shih; M O Weeks; P Gruss; R Dhar; S Oroszlan; E M Scolnick
Journal: J Virol Date: 1982-04 Impact factor: 5.103

9. Characterization of the phosphorylation sites and the surrounding amino acid sequences of the p21 transforming proteins coded for by the Harvey and Kirsten strains of murine sarcoma viruses.

Authors: T Y Shih; P E Stokes; G W Smythers; R Dhar; S Oroszlan
Journal: J Biol Chem Date: 1982-10-10 Impact factor: 5.157

10. Saccharomyces cerevisiae cdc15 mutants arrested at a late stage in anaphase are rescued by Xenopus cDNAs encoding N-ras or a protein with beta-transducin repeats.

Authors: W Spevak; B D Keiper; C Stratowa; M J Castañón
Journal: Mol Cell Biol Date: 1993-08 Impact factor: 4.272

Nucleotide sequence of two rasH related-genes isolated from the yeast Saccharomyces cerevisiae.

1. A new method for sequencing DNA.

2. Mechanism of activation of a human oncogene.

3. Transcription terminates in yeast distal to a control sequence.

4. Acquisition of transforming properties by alternative point mutations within c-bas/has human proto-oncogene.

5. Proposal for naming host cell-derived inserts in retrovirus genomes.

6. A point mutation is responsible for the acquisition of transforming properties by the T24 human bladder carcinoma oncogene.

7. Saccharomyces cerevisiae synthesizes proteins related to the p21 gene product of ras genes found in mammals.

8. Identification of a precursor in the biosynthesis of the p21 transforming protein of harvey murine sarcoma virus.

9. Characterization of the phosphorylation sites and the surrounding amino acid sequences of the p21 transforming proteins coded for by the Harvey and Kirsten strains of murine sarcoma viruses.

10. Evidence for an intron-contained sequence required for the splicing of yeast RNA polymerase II transcripts.

1. SRA5 encodes the low-Km cyclic AMP phosphodiesterase of Saccharomyces cerevisiae.

2. Ras history: The saga continues.

3. GTP-binding domain: three consensus sequence elements with distinct spacing.

4. Transcriptional regulatory elements of the RAS2 gene of Saccharomyces cerevisiae.

5. The cloning and characterization of a RAS gene from Schizosaccharomyces pombe.

Review 6. RAS genes and growth control in Saccharomyces cerevisiae.

7. Expression of ras cellular oncogenes during development of Drosophila melanogaster.

8. Yeast omnipotent supressor SUP1 (SUP45): nucleotide sequence of the wildtype and a mutant gene.

9. Carbon source regulation of RAS1 expression in Saccharomyces cerevisiae and the phenotypes of ras2- cells.

10. Saccharomyces cerevisiae cdc15 mutants arrested at a late stage in anaphase are rescued by Xenopus cDNAs encoding N-ras or a protein with beta-transducin repeats.