| Literature DB >> 6325443 |
L S Harman, C Mottley, R P Mason.
Abstract
The oxidation of L-cysteine by horseradish peroxidase in the presence of oxygen forms a thiyl free radical as demonstrated with the spin-trapping ESR technique. Reactions of this thiyl free radical result in oxygen consumption, which is inhibited by the spin trap 5,5'-dimethyl-1-pyrroline-N-oxide. Cysteine sulfinic acid, a cysteine metabolite, is a poorer substrate for horseradish peroxidase than cysteine and is oxidized to form both sulfur-centered and carbon-centered free radicals.Entities:
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Year: 1984 PMID： 6325443
Source DB: PubMed Journal: J Biol Chem ISSN： 0021-9258 Impact factor: 5.157