Literature DB >> 18991755

Antioxidant therapy in Alzheimer's disease: theory and practice.

Gjumrakch Aliev1, Mark E Obrenovich, V Prakash Reddy, Justin C Shenk, Paula I Moreira, Akihiko Nunomura, Xiongwei Zhu, Mark A Smith, George Perry.   

Abstract

Alzheimer disease treatment has yet to yield a successful therapy that addresses the source of the damage found in brains. Of the varied proposed theories of AD etiology, reactive oxygen species (ROS) generation is cited as a common factor. Efforts to reduce the pathology associated with ROS via antioxidants therefore offer new hope to patients suffering from this devastative disease.

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Year:  2008        PMID： 18991755      PMCID： PMC2921812          DOI： 10.2174/138955708786369582

Source DB:  PubMed          Journal:  Mini Rev Med Chem        ISSN： 1389-5575            Impact factor:   3.862


  178 in total

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Authors:  B Moosmann; C Behl
Journal:  Proc Natl Acad Sci U S A       Date:  1999-08-03       Impact factor: 11.205

Review 2.  Epidemiology of neurodegeneration.

Authors:  Richard Mayeux
Journal:  Annu Rev Neurosci       Date:  2003-01-24       Impact factor: 12.449

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Authors:  Howard L Weiner; Dennis J Selkoe
Journal:  Nature       Date:  2002 Dec 19-26       Impact factor: 49.962

4.  Low education and childhood rural residence: risk for Alzheimer's disease in African Americans.

Authors:  K S Hall; S Gao; F W Unverzagt; H C Hendrie
Journal:  Neurology       Date:  2000-01-11       Impact factor: 9.910

5.  Chronic antioxidant treatment improves the cognitive performance of aged rats.

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Journal:  Brain Res       Date:  1995-09-25       Impact factor: 3.252

6.  4-Hydroxynonenal-derived advanced lipid peroxidation end products are increased in Alzheimer's disease.

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Journal:  J Neurochem       Date:  1997-05       Impact factor: 5.372

7.  A controlled study of 2 doses of idebenone in the treatment of Alzheimer's disease.

Authors:  G Weyer; R M Babej-Dölle; D Hadler; S Hofmann; W M Herrmann
Journal:  Neuropsychobiology       Date:  1997       Impact factor: 2.328

8.  Binding of human apolipoprotein E to synthetic amyloid beta peptide: isoform-specific effects and implications for late-onset Alzheimer disease.

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Journal:  Proc Natl Acad Sci U S A       Date:  1993-09-01       Impact factor: 11.205

9.  Alzheimer's and Parkinson's disease. Brain levels of glutathione, glutathione disulfide, and vitamin E.

Authors:  J D Adams; L K Klaidman; I N Odunze; H C Shen; C A Miller
Journal:  Mol Chem Neuropathol       Date:  1991-06

Review 10.  Radical AGEing in Alzheimer's disease.

Authors:  M A Smith; L M Sayre; V M Monnier; G Perry
Journal:  Trends Neurosci       Date:  1995-04       Impact factor: 13.837
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  38 in total

Review 1.  Natural products as a source of Alzheimer's drug leads.

Authors:  Philip Williams; Analia Sorribas; Melanie-Jayne R Howes
Journal:  Nat Prod Rep       Date:  2010-11-12       Impact factor: 13.423

Review 2.  Calcium's role as nuanced modulator of cellular physiology in the brain.

Authors:  Hilaree N Frazier; Shaniya Maimaiti; Katie L Anderson; Lawrence D Brewer; John C Gant; Nada M Porter; Olivier Thibault
Journal:  Biochem Biophys Res Commun       Date:  2016-08-20       Impact factor: 3.575

3.  Inhibition of NADPH oxidase promotes alternative and anti-inflammatory microglial activation during neuroinflammation.

Authors:  Sang-Ho Choi; Saba Aid; Hyung-Wook Kim; Sharon H Jackson; Francesca Bosetti
Journal:  J Neurochem       Date:  2011-11-28       Impact factor: 5.372

Review 4.  Nootropic and Anti-Alzheimer's Actions of Medicinal Plants: Molecular Insight into Therapeutic Potential to Alleviate Alzheimer's Neuropathology.

Authors:  Md Sahab Uddin; Abdullah Al Mamun; Md Tanvir Kabir; Md Jakaria; Bijo Mathew; George E Barreto; Ghulam Md Ashraf
Journal:  Mol Neurobiol       Date:  2018-11-09       Impact factor: 5.590

5.  Frontiers in Alzheimer's disease therapeutics.

Authors:  Jeremy G Stone; Gemma Casadesus; Kasia Gustaw-Rothenberg; Sandra L Siedlak; Xinglong Wang; Xiongwei Zhu; George Perry; Rudy J Castellani; Mark A Smith
Journal:  Ther Adv Chronic Dis       Date:  2011-01-01       Impact factor: 5.091

6.  Comparison of Neuroprotective Effects of Melissa officinalis Total Extract and Its Acidic and Non-Acidic Fractions against A β-Induced Toxicity.

Authors:  Mohammad Reza Sepand; Maliheh Soodi; Homa Hajimehdipoor; Masoud Soleimani; Ehsan Sahraei
Journal:  Iran J Pharm Res       Date:  2013       Impact factor: 1.696

Review 7.  Current Update on Synopsis of miRNA Dysregulation in Neurological Disorders.

Authors:  Mohammad A Kamal; Gohar Mushtaq; Nigel H Greig
Journal:  CNS Neurol Disord Drug Targets       Date:  2015       Impact factor: 4.388

Review 8.  Neurodegenerative disorders and nanoformulated drug development.

Authors:  Ari Nowacek; Lisa M Kosloski; Howard E Gendelman
Journal:  Nanomedicine (Lond)       Date:  2009-07       Impact factor: 5.307

9.  Euxanthone Attenuates Aβ1-42-Induced Oxidative Stress and Apoptosis by Triggering Autophagy.

Authors:  Haicheng Yuan; Chuanwu Jiang; Jingde Zhao; Yunsheng Zhao; Yongbin Zhang; Yanqi Xu; Xiaoning Gao; Lingfei Guo; Yongji Liu; Kai Liu; Bo Xu; Gang Sun
Journal:  J Mol Neurosci       Date:  2018-10-22       Impact factor: 3.444

10.  Amentoflavone Ameliorates Aβ1-42-Induced Memory Deficits and Oxidative Stress in Cellular and Rat Model.

Authors:  Chao Chen; Bin Li; Guangqing Cheng; Xiaoni Yang; Ningning Zhao; Ran Shi
Journal:  Neurochem Res       Date:  2018-02-06       Impact factor: 3.996
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