Literature DB >> 6324383

Systemic combination chemotherapy as primary treatment of brain metastasis from lung cancer.

H Kantarjian, P A Farha, G Spitzer, W K Murphy, M Valdivieso.   

Abstract

Five patients with primary lung cancer metastatic to the brain were treated with systemic combination therapy alone. One patient had had unsuccessful radiation therapy, while the other four received chemotherapy as the primary modality of treatment. Response was observed in all five patients. The concept of the blood-brain barrier and the role of systemic chemotherapy in metastatic cancer to the brain are discussed.

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Year:  1984        PMID： 6324383     DOI： 10.1097/00007611-198404000-00005

Source DB:  PubMed          Journal:  South Med J        ISSN： 0038-4348            Impact factor:   0.954


  6 in total

Review 1.  A critique of the role of the blood-brain barrier in the chemotherapy of human brain tumors.

Authors:  D J Stewart
Journal:  J Neurooncol       Date:  1994       Impact factor: 4.130

2.  The response of cerebral metastases in small cell lung cancer to systemic chemotherapy.

Authors:  C J Twelves; R L Souhami; P G Harper; C M Ash; S G Spiro; H M Earl; J S Tobias; H Quinn; D M Geddes
Journal:  Br J Cancer       Date:  1990-01       Impact factor: 7.640

3.  The value of computed tomographic (CT) scan surveillance in the detection and management of brain metastases in patients with small cell lung cancer.

Authors:  J Hardy; I Smith; G Cherryman; M Vincent; I Judson; T Perren; M Williams
Journal:  Br J Cancer       Date:  1990-10       Impact factor: 7.640

4.  A pilot study of concurrent whole-brain radiotherapy and chemotherapy combined with cisplatin, vindesine and mitomycin in non-small-cell lung cancer with brain metastasis.

Authors:  K Furuse; T Kamimori; M Kawahara; N Kodama; M Ogawara; S Atagi; N Naka; M Akira; K Kubota
Journal:  Br J Cancer       Date:  1997       Impact factor: 7.640

Review 5.  Targeted drugs for systemic therapy of lung cancer with brain metastases.

Authors:  Ya-Wen Sun; Jian Xu; Jun Zhou; Wen-Juan Liu
Journal:  Oncotarget       Date:  2017-12-22

6.  Factors affecting platinum concentrations in human surgical tumour specimens after cisplatin.

Authors:  D J Stewart; J M Molepo; R M Green; V A Montpetit; H Hugenholtz; A Lamothe; N Z Mikhael; M D Redmond; M Gadia; R Goel
Journal:  Br J Cancer       Date:  1995-03       Impact factor: 7.640
  6 in total

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