Literature DB >> 6324237

Human natural cytotoxic cell activity: enhancement by leukotrienes (LT) A4, B4 and D4, but not by stereoisomers of LTB4 or HETES.

M Rola-Pleszczynski, L Gagnon, M Rudzinska, P Borgeat, P Sirois.   

Abstract

Natural cytotoxic activity of human lymphocytes was significantly enhanced by incubation with LTA4, LTB4 or LTD4. In contrast, stereoisomers of LTB4 as well as 5-HETE and 12-HETE were not active. These findings suggest that leukotrienes may play an important role in host defense mechanisms.

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Year:  1984        PMID： 6324237     DOI： 10.1016/0262-1746(84)90111-2

Source DB:  PubMed          Journal:  Prostaglandins Leukot Med        ISSN： 0262-1746


  3 in total

1.  Indomethacin stimulation of macrophage cytostasis against MOPC-315 tumor cells is inhibited by both prostaglandin E2 and nordihydroguaiaretic acid, a lipoxygenase inhibitor.

Authors:  G R Elliott; C Tak; C Pellens; S Ben-Efraim; I L Bonta
Journal:  Cancer Immunol Immunother       Date:  1988       Impact factor: 6.968

Review 2.  The potential pathophysiological role of platelet-activating factor in human diseases.

Authors:  C Kroegel
Journal:  Klin Wochenschr       Date:  1988-05-02

3.  Differential Contribution of BLT1 and BLT2 to Leukotriene B4-Induced Human NK Cell Cytotoxicity and Migration.

Authors:  Meng Wang; Nermine Mostafa El-Maghraby; Sylvie Turcotte; Marek Rola-Pleszczynski; Jana Stankova
Journal:  Mediators Inflamm       Date:  2015-12-01       Impact factor: 4.711
  3 in total

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