Literature DB >> 6322502

Preliminary report on progesterone effect on peripheral estrone sulfate metabolism.

V M Jasonni, C Bulletti, F Franceschetti, P Ciotti, M Bonavia, A P Ferraretti, C Flamigni.   

Abstract

The effect of progesterone (P) on peripheral estrone sulfate (E1S) was investigated in postmenopausal women using E1S constant infusions. The metabolic clearance rate of E1S (MCRE1S) was significantly lowered by P administration (p less than 0.01), while no significant changes were observed for E1S----E1 conversion ratio. The present findings suggest that P can affect the E1S peripheral fate inducing deep changes in estrogen equilibrium.

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Year:  1983        PMID: 6322502

Source DB:  PubMed          Journal:  Acta Eur Fertil        ISSN: 0587-2421


  1 in total

1.  Increases in serum estrone sulfate level are associated with increased mammographic density during menopausal hormone therapy.

Authors:  Carolyn J Crandall; Min Guan; Gail A Laughlin; Giske A Ursin; Frank Z Stanczyk; Sue A Ingles; Elizabeth Barrett-Connor; Gail A Greendale
Journal:  Cancer Epidemiol Biomarkers Prev       Date:  2008-07       Impact factor: 4.254

  1 in total

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