Literature DB >> 6320499

A comparative study on cytotoxicities and biochemical properties of anthraquinone mycotoxins emodin and skyrin from Penicillium islandicum Sopp.

K Kawai, T Kato, H Mori, J Kitamura, Y Nozawa.   

Abstract

The anthraquinone mycotoxins emodin and skyrin were examined for the inhibitory effects on murine leukemia L1210 culture cells, oxidative phosphorylation of rat liver mitochondria, and Na+, K+-activated ATPase activity of rat brain microsomes to find the differences between their modes of toxic action. Skyrin exhibited a stronger inhibitory effect than emodin on the growth of L1210 culture cells. Emodin showed a stronger uncoupling effect than skyrin on mitochondrial respiration. Skyrin inhibited Na+, K+-activated ATPase activity of rat brain microsomes but emodin did not inhibit.

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Year:  1984        PMID： 6320499     DOI： 10.1016/0378-4274(84)90141-3

Source DB:  PubMed          Journal:  Toxicol Lett        ISSN： 0378-4274            Impact factor:   4.372


  11 in total

1.  Polyphasic taxonomy of the genus Talaromyces.

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Journal:  Stud Mycol       Date:  2014-06       Impact factor: 16.097

2.  Reexamination of respiration-impairing effect of bikaverin on isolated mitochondria.

Authors:  T Suzuki; A Kitagawa; K Kawai; T Hamasaki
Journal:  Mycotoxin Res       Date:  1998-03       Impact factor: 3.833

Review 3.  Experimental and theoretical studies of emodin interacting with a lipid bilayer of DMPC.

Authors:  Antonio R da Cunha; Evandro L Duarte; Hubert Stassen; M Teresa Lamy; Kaline Coutinho
Journal:  Biophys Rev       Date:  2017-09-22

4.  Inhibition of electron transfer and uncoupling effects by emodin and emodinanthrone in Escherichia coli.

Authors:  T Ubbink-Kok; J A Anderson; W N Konings
Journal:  Antimicrob Agents Chemother       Date:  1986-07       Impact factor: 5.191

5.  Genotoxicity in the hepatocyte/DNA repair test and toxicity to liver mitochondria of 1-hydroxyanthraquinone and several dihydroxyanthraquinones.

Authors:  K Kawai; H Mori; S Sugie; N Yoshimi; T Inoue; T Nakamaru; Y Nozawa; T Matsushima
Journal:  Cell Biol Toxicol       Date:  1986-12       Impact factor: 6.691

6.  The interaction of rubroskyrin, a modified bis-anthraquinone pigment fromPenicillium islandicum Sopp, with respiratory chain of liver mitochondria.

Authors:  S Mori; K Kawai; Y Nozawa; Y Ogihara
Journal:  Mycotoxin Res       Date:  1997-03       Impact factor: 3.833

7.  Emodin ameliorates high-glucose induced mesangial p38 over-activation and hypocontractility via activation of PPARgamma.

Authors:  Yi Liu; Lei Jia; Zun Chang Liu; Hong Zhang; Peng Ju Zhang; Qiang Wan; Rong Wang
Journal:  Exp Mol Med       Date:  2009-09-30       Impact factor: 8.718

8.  Recent Progress in the Use of Glucagon and Glucagon Receptor Antago-nists in the Treatment of Diabetes Mellitus.

Authors:  Mohamed Lotfy; Huba Kalasz; Gyorgy Szalai; Jaipaul Singh; Ernest Adeghate
Journal:  Open Med Chem J       Date:  2014-12-31

9.  Taxonomic re-evaluation of species in Talaromyces section Islandici, using a polyphasic approach.

Authors:  N Yilmaz; C M Visagie; J C Frisvad; J Houbraken; K Jacobs; R A Samson
Journal:  Persoonia       Date:  2015-05-19       Impact factor: 11.051

10.  Anti-Biofilm and Antivirulence Activities of Metabolites from Plectosphaerella cucumerina against Pseudomonas aeruginosa.

Authors:  Jinwei Zhou; Shiyuan Bi; Hongjuan Chen; Tongtong Chen; Rui Yang; Minghui Li; Yonghong Fu; Ai-Qun Jia
Journal:  Front Microbiol       Date:  2017-05-03       Impact factor: 5.640
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