Literature DB >> 6318707

Identification and quantitation of arachidonic-acid metabolic products in rabbit, rat and human saliva.

B Rigas, R A Lewis, K F Austen, E J Corey, L Levine.   

Abstract

Arachidonic-acid metabolites were identified in salivary secretions of rabbits, rats and man and in homogenates of rabbit parotid and submandibular glands. The following levels were determined in mixed saliva of healthy volunteers: PGE2, 0.65 +/- 0.8 ng/ml; PGF2 alpha, 0.41 +/- 0.06 ng/ml; serologically active hydroxyeicosatetraenoic acids (HETE) 319.6 +/- 36.6 ng/ml; serologically active 6-sulphidopeptide-containing leukotrienes 1.72 +/- 0.21 ng/ml (all values mean +/- SEM). In all instances, HETE markedly predominated over all other arachidonic-acid metabolites.

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Year:  1983        PMID: 6318707     DOI: 10.1016/0003-9969(83)90058-4

Source DB:  PubMed          Journal:  Arch Oral Biol        ISSN: 0003-9969            Impact factor:   2.633


  5 in total

1.  Detection of sputum eicosanoids in cystic fibrosis and in normal saliva by bioassay and radioimmunoassay.

Authors:  J T Zakrzewski; N C Barnes; P J Piper; J F Costello
Journal:  Br J Clin Pharmacol       Date:  1987-01       Impact factor: 4.335

2.  Salivary eicosanoid concentration in patients with Sjögren's syndrome.

Authors:  M Tishler; I Yaron; A Raz; F A Meyer; M Yaron
Journal:  Ann Rheum Dis       Date:  1996-03       Impact factor: 19.103

3.  Dietary menhaden oil lowers plasma prostaglandins and calcium in mice bearing the prostaglandin-producing HSDM1 fibrosarcoma.

Authors:  A H Tashjian; E F Voelkel; D R Robinson; L Levine
Journal:  J Clin Invest       Date:  1984-12       Impact factor: 14.808

4.  Arachidonic acid, prostaglandin E2 and leukotriene C4 levels in gingiva and submandibular salivary glands of rats fed diets containing n-3 fatty acids.

Authors:  S Q Alam; B M Bergens; B S Alam
Journal:  Lipids       Date:  1991-11       Impact factor: 1.880

5.  The oral cavity and age: a site of chronic inflammation?

Authors:  Magnus Bäck; Hanna Hlawaty; Carlos Labat; Jean-Baptiste Michel; Charles Brink
Journal:  PLoS One       Date:  2007-12-26       Impact factor: 3.240

  5 in total

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