| Literature DB >> 6317429 |
Abstract
Preganglionic nerve stimulation or elevated [K+]o increase cAMP levels in isolated guinea-pig superior cervical ganglia, a ganglion lacking adrenergic inhibitory synaptic potentials. The cAMP response to K+ and nerve stimulation is not prevented by atropine or phentolamine. The regulation of cAMP content does not involve cholinergic or adrenergic mechanism. Of polypeptides tested, only VIP (5 X 10(-6) M) increases cAMP content to the extent observed with preganglionic nerve stimulation.Entities:
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Year: 1983 PMID: 6317429 DOI: 10.1007/bf01990094
Source DB: PubMed Journal: Experientia ISSN: 0014-4754