Literature DB >> 6317109

The beta-adrenoceptor of pig coronary arteries: determination of beta 1 and beta 2 subtypes by radioligand binding.

J Schwartz, J Velly.   

Abstract

beta-Adrenoceptors of pig coronary arteries were investigated by the use of a new ligand, 125iodocyanopindolol (ICYP) in binding studies. Inhibition of ICYP binding by betaxolol (a selective beta 1-antagonist), zinterol (a selective beta 2-agonist) and ICI 118551 (a selective beta 2-blocking drug) resulted in non-linear Scatchard plots, suggesting that both beta-adrenoceptor subtypes are present in pig coronary arteries. Computer analysis of the data gave a beta 1:beta 2-adrenoceptor ratio of approximately 65:35.

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Year:  1983        PMID： 6317109      PMCID： PMC2044863          DOI： 10.1111/j.1476-5381.1983.tb11013.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  20 in total

1.  [3H]Dihydroergocryptine binding to alpha adrenergic receptors in canine aortic membranes.

Authors:  B S Tsai; R J Lefkowitz
Journal:  J Pharmacol Exp Ther       Date:  1978-03       Impact factor: 4.030

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Authors:  C J Limas; C Limas
Journal:  Biochim Biophys Acta       Date:  1979-02-01

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Authors:  J R Sporn; P B Molinoff
Journal:  J Cyclic Nucleotide Res       Date:  1976

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Authors:  G D Baron; R N Speden; D F Bohr
Journal:  Am J Physiol       Date:  1972-10

5.  Characterization of the adrenoceptors in coronary arteries of pigs.

Authors:  B L Bayer; P Mentz; W Förster
Journal:  Eur J Pharmacol       Date:  1974-11       Impact factor: 4.432

Review 6.  Pharmacological aspects of the coronary circulation.

Authors:  J R Parratt
Journal:  Prog Med Chem       Date:  1969

7.  The application of multicompartmental analysis to problems of clinical medicine. Combined clinical staff conference at the National Institutes of Health.

Authors:  N I Berlin; M Berman; P D Berk; J M Phang; T A Waldmann
Journal:  Ann Intern Med       Date:  1968-02       Impact factor: 25.391

8.  The beta-adrenoceptors in the smooth muscle of pig coronary arteries.

Authors:  B Johansson
Journal:  Eur J Pharmacol       Date:  1973-11       Impact factor: 4.432

9.  Differentiation of receptor systems activated by sympathomimetic amines.

Authors:  A M Lands; A Arnold; J P McAuliff; F P Luduena; T G Brown
Journal:  Nature       Date:  1967-05-06       Impact factor: 49.962

10.  Characterization of the coronary vascular -adrenoceptor in the pig.

Authors:  G M Drew; G P Levy
Journal:  Br J Pharmacol       Date:  1972-10       Impact factor: 8.739
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  8 in total

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2.  Proceedings of the British Pharmacological Society. Leeds, 12th-14th July 1989. Abstracts.

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Journal:  Br J Pharmacol       Date:  1989-10       Impact factor: 8.739

3.  Beta-adrenoceptors of the human myocardium: determination of beta 1 and beta 2 subtypes by radioligand binding.

Authors:  A Heitz; J Schwartz; J Velly
Journal:  Br J Pharmacol       Date:  1983-12       Impact factor: 8.739

4.  Autoradiographic analysis of the distribution of beta-adrenoceptors in the dog splenic vasculature.

Authors:  S Lipe; R J Summers
Journal:  Br J Pharmacol       Date:  1986-03       Impact factor: 8.739

5.  Beta 1- and beta 2-adrenoceptor binding and functional response in right and left atria of rat heart.

Authors:  E N Juberg; K P Minneman; P W Abel
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1985-09       Impact factor: 3.000

6.  β-Adrenergic-mediated vasodilation in young men and women: cyclooxygenase restrains nitric oxide synthase.

Authors:  Jacqueline K Limberg; Rebecca E Johansson; Garrett L Peltonen; John W Harrell; J Mikhail Kellawan; Marlowe W Eldridge; Joshua J Sebranek; William G Schrage
Journal:  Am J Physiol Heart Circ Physiol       Date:  2016-01-08       Impact factor: 4.733

7.  Determination of infundibular innervation and amine receptor content in cyanotic and acyanotic myocardium: relation to clinical events in tetralogy of Fallot.

Authors:  L B McGrath; C Chen; J Gu; J Bianchi; J M Levett
Journal:  Pediatr Cardiol       Date:  1991-07       Impact factor: 1.655

8.  Clinical and morphological characteristics of head-facial haemangiomas.

Authors:  Giorgio Iannetti; Andrea Torroni; Stefano Chiummariello; Carlo Cavallotti
Journal:  Head Face Med       Date:  2007-02-23       Impact factor: 2.151
  8 in total

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