Literature DB >> 6310751

Human milk kills parasitic intestinal protozoa.

F D Gillin, D S Reiner, C S Wang.   

Abstract

Giardia lamblia, a common pathogenic intestinal parasite of humans, was rapidly killed by exposure to normal human milk in vitro. The killing did not depend on secretory immunoglobulin A. Entamoeba histolytica, the dysentery amoeba, was also killed by normal human milk. Giardia-cidal activity cochromatographed with an unusual lipase that is present in the milk of humans but not of lower mammals. Human milk may play a protective role in infants exposed to this parasite.

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Year:  1983        PMID: 6310751     DOI: 10.1126/science.6310751

Source DB:  PubMed          Journal:  Science        ISSN: 0036-8075            Impact factor:   47.728


  19 in total

1.  The effects of saturated fatty acids on Giardia duodenalis trophozoites in vitro.

Authors:  Paran Rayan; Deborah Stenzel; Pauline Ann McDonnell
Journal:  Parasitol Res       Date:  2005-07-01       Impact factor: 2.289

2.  Amoebicidal activity of milk, apo-lactoferrin, sIgA and lysozyme.

Authors:  Nidia León-Sicairos; Fernando López-Soto; Magda Reyes-López; Delfino Godínez-Vargas; Cynthia Ordaz-Pichardo; Mireya de la Garza
Journal:  Clin Med Res       Date:  2006-06

Review 3.  Immune response to Giardia duodenalis.

Authors:  G Faubert
Journal:  Clin Microbiol Rev       Date:  2000-01       Impact factor: 26.132

4.  Antiviral and antibacterial lipids in human milk and infant formula feeds.

Authors:  C E Isaacs; S Kashyap; W C Heird; H Thormar
Journal:  Arch Dis Child       Date:  1990-08       Impact factor: 3.791

5.  Killing of Giardia lamblia by human milk is mediated by unsaturated fatty acids.

Authors:  L Rohrer; K H Winterhalter; J Eckert; P Köhler
Journal:  Antimicrob Agents Chemother       Date:  1986-08       Impact factor: 5.191

6.  Apoptosis induced by a human milk protein.

Authors:  A Håkansson; B Zhivotovsky; S Orrenius; H Sabharwal; C Svanborg
Journal:  Proc Natl Acad Sci U S A       Date:  1995-08-15       Impact factor: 11.205

7.  Cholate-dependent killing of Giardia lamblia by human milk.

Authors:  F D Gillin; D S Reiner; M J Gault
Journal:  Infect Immun       Date:  1985-03       Impact factor: 3.441

8.  Immunocytochemical localization of pancreatic carboxylic ester hydrolase in human paneth cells.

Authors:  P Lechene de la Porte; H Lafont; D Lombardo
Journal:  Histochemistry       Date:  1986

Review 9.  The biology of Giardia spp.

Authors:  R D Adam
Journal:  Microbiol Rev       Date:  1991-12

10.  The old and new therapeutic approaches to the treatment of giardiasis: where are we?

Authors:  Haendel G N O Busatti; Joseph F G Santos; Maria A Gomes
Journal:  Biologics       Date:  2009-07-13
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