Literature DB >> 6310152

Relationship between synthesis and cleavage of poliovirus-specific proteins.

A A Thomas, H O Voorma, A Boeye.   

Abstract

Poliovirus proteinase was studied in vitro in lysates from poliovirus-infected HeLa cells. Preincubation of these lysates caused (i) a reduction in poliovirus proteinase activity and (ii) a partial dependence on exogenous mRNA for optimal translation. Proteins translated from endogenous poliovirus RNA in preincubated extracts from virus-infected HeLa cells are poorly cleaved. This cleavage deficiency is alleviated by adding fresh poliovirus RNA to the translation system, thus, allowing re-initiation to occur. This suggests that the poliovirus proteinase is highly unstable.

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Year:  1983        PMID： 6310152      PMCID： PMC255348     

Source DB:  PubMed          Journal:  J Virol        ISSN： 0022-538X            Impact factor:   5.103


  18 in total

1.  Capping of eucaryotic mRNAs.

Authors:  A J Shatkin
Journal:  Cell       Date:  1976-12       Impact factor: 41.582

2.  Translation of poliovirus RNA in vitro: detection of two different initiation sites.

Authors:  M L Celma; E Ehrenfeld
Journal:  J Mol Biol       Date:  1975-11-15       Impact factor: 5.469

3.  Translation of encephalomyocarditis virus RNA in vitro yields an active proteolytic processing enzyme.

Authors:  H R Pelham
Journal:  Eur J Biochem       Date:  1978-04-17

4.  Cell-free synthesis and processing of the proteins of poliovirus.

Authors:  D S Shih; C T Shih; O Kew; M Pallansch; R Rueckert; P Kaesberg
Journal:  Proc Natl Acad Sci U S A       Date:  1978-12       Impact factor: 11.205

5.  A film detection method for tritium-labelled proteins and nucleic acids in polyacrylamide gels.

Authors:  W M Bonner; R A Laskey
Journal:  Eur J Biochem       Date:  1974-07-01

6.  Cleavage of structural proteins during the assembly of the head of bacteriophage T4.

Authors:  U K Laemmli
Journal:  Nature       Date:  1970-08-15       Impact factor: 49.962

7.  An efficient mRNA-dependent translation system from reticulocyte lysates.

Authors:  H R Pelham; R J Jackson
Journal:  Eur J Biochem       Date:  1976-08-01

8.  Rapid method for the preparation of encephalomyocarditis virus protease from rabbit reticulocyte lysates.

Authors:  C Y Shih; N Naseer; D S Shih
Journal:  J Virol       Date:  1982-06       Impact factor: 5.103

9.  A protein linked to the 5' termini of both RNA components of the cowpea mosaic virus genome.

Authors:  J Stanley; P Rottier; J W Davies; P Zabel; A Van Kammen
Journal:  Nucleic Acids Res       Date:  1978-12       Impact factor: 16.971

10.  Proteolytic processing of poliovirus polypeptides: antibodies to polypeptide P3-7c inhibit cleavage at glutamine-glycine pairs.

Authors:  R Hanecak; B L Semler; C W Anderson; E Wimmer
Journal:  Proc Natl Acad Sci U S A       Date:  1982-07       Impact factor: 11.205
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  1 in total

Review 1.  The ubiquitin-proteasome system in positive-strand RNA virus infection.

Authors:  Alex GoEun Choi; Jerry Wong; David Marchant; Honglin Luo
Journal:  Rev Med Virol       Date:  2012-07-11       Impact factor: 6.989
  1 in total

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