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Literature DB >> 6307330

Delta-9-tetrahydrocannabinol and gastric emptying.

Abstract

The effects of delta-9-tetrahydrocannabinol (0.5 and 1 mg i.v.) on gastric emptying of liquid were investigated in seven normal volunteers and compared with placebo. Despite significant change in pulse rate and psychological parameters consistent with cannabis activity there was no significant effect on the pattern of gastric emptying. It is therefore suggested that an anti-emetic action of delta-9-tetrahydrocannabinol does not involve a change in gastric emptying.

Entities: Chemical

Mesh：

Substances：
Dronabinol

Year: 1983 PMID： 6307330 PMCID： PMC1427915 DOI： 10.1111/j.1365-2125.1983.tb01561.x

Source DB: PubMed Journal: Br J Clin Pharmacol ISSN： 0306-5251 Impact factor: 4.335

12 in total

1. Effects of delta-9-tetrahydrocannabinol on drug distribution and metabolism. Antipyrine, pentobarbital, and ethanol.

Authors: N L Benowitz; R T Jones
Journal: Clin Pharmacol Ther Date: 1977-09 Impact factor: 6.875

2. Antiemetics: neurotransmitter receptor binding predicts therapeutic actions.

Authors: S J Peroutka; S H Snyder
Journal: Lancet Date: 1982-03-20 Impact factor: 79.321

3. Amelioration of cancer chemotherapy-induced nausea and vomiting by delta-9-tetrahydrocannabinol.

Authors: H Ekert; K D Waters; I H Jurk; J Mobilia; P Loughnan
Journal: Med J Aust Date: 1979-12-15 Impact factor: 7.738

4. The effect of cannabinoids on intestinal motility and their antinociceptive effect in mice.

Authors: G B Chesher; C J Dahl; M Everingham; D M Jackson; H Marchant-Williams; G A Starmer
Journal: Br J Pharmacol Date: 1973-12 Impact factor: 8.739

5. Delata-9-tetrahydrocannabinol as an antiemetic in cancer patients receiving high-dose methotrexate. A prospective, randomized evaluation.

Authors: A E Chang; D J Shiling; R C Stillman; N H Goldberg; C A Seipp; I Barofsky; R M Simon; S A Rosenberg
Journal: Ann Intern Med Date: 1979-12 Impact factor: 25.391

6. Plasma delta-9 tetrahydrocannabinol concentrations and clinical effects after oral and intravenous administration and smoking.

Authors: A Ohlsson; J E Lindgren; A Wahlen; S Agurell; L E Hollister; H K Gillespie
Journal: Clin Pharmacol Ther Date: 1980-09 Impact factor: 6.875

7. Antiemetics in patients receiving chemotherapy for cancer: a randomized comparison of delta-9-tetrahydrocannabinol and prochlorperazine.

Authors: S E Sallan; C Cronin; M Zelen; N E Zinberg
Journal: N Engl J Med Date: 1980-01-17 Impact factor: 91.245

8. Antagonism of cisplatin induced emesis in the dog.

Authors: J A Gylys; K M Doran; J P Buyniski
Journal: Res Commun Chem Pathol Pharmacol Date: 1979-01

9. The seed and the soil: effect of dosage, personality and starting state on the response to delta 9 tetrahydrocannabinol in man.

Authors: H Ashton; J Golding; V R Marsh; J E Millman; J W Thompson
Journal: Br J Clin Pharmacol Date: 1981-11 Impact factor: 4.335

10. delta 9-tetrahydrocannabinol in clinical oncology.

Authors: D S Poster; J S Penta; S Bruno; J S Macdonald
Journal: JAMA Date: 1981 May 22-29 Impact factor: 56.272

3 in total

Review 1. Cannabinoids and the gastrointestinal tract.

Authors: R G Pertwee
Journal: Gut Date: 2001-06 Impact factor: 23.059

2. Marijuana Use in Patients with Symptoms of Gastroparesis: Prevalence, Patient Characteristics, and Perceived Benefit.

Authors: Henry P Parkman; Emily P Sharkey; Linda A Nguyen; Katherine P Yates; Thomas L Abell; William L Hasler; William Snape; John Clarke; Ron Schey; Kenneth L Koch; Braden Kuo; Richard W McCallum; Irene Sarosiek; Madhusudan Grover; Gianrico Farrugia; James Tonascia; Pankaj J Pasricha
Journal: Dig Dis Sci Date: 2019-11-22 Impact factor: 3.199

Review 3. Review: The Role of Cannabinoids on Esophageal Function-What We Know Thus Far.

Authors: Jonathan Gotfried; Rahul Kataria; Ron Schey
Journal: Cannabis Cannabinoid Res Date: 2017-10-01

3 in total