Literature DB >> 231736

Amelioration of cancer chemotherapy-induced nausea and vomiting by delta-9-tetrahydrocannabinol.

H Ekert, K D Waters, I H Jurk, J Mobilia, P Loughnan.   

Abstract

The antinausea and antivomiting effects of delta-9-tetrahydrocannabinol (THC) in children receiving cancer chemotherapy were compared with those of metoclopramide syrup and prochlorperazine tablets in two double-blind studies. THC was found to be a significantly better antinausea and antivomiting agent, but not all patients obtained relief of nausea and vomiting with THC. In some patients, THC enhanced appetite during a course of chemotherapy. In two patients, a "high" associated with THC administrationwas reported. Drowsiness was reported significantly more frequently with THC.

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Year:  1979        PMID: 231736

Source DB:  PubMed          Journal:  Med J Aust        ISSN: 0025-729X            Impact factor:   7.738


  26 in total

Review 1.  Cannabinoids for control of chemotherapy induced nausea and vomiting: quantitative systematic review.

Authors:  M R Tramèr; D Carroll; F A Campbell; D J Reynolds; R A Moore; H J McQuay
Journal:  BMJ       Date:  2001-07-07

Review 2.  The Use of Cannabinoids in Treating Dementia.

Authors:  Megan Weier; Wayne Hall
Journal:  Curr Neurol Neurosci Rep       Date:  2017-08       Impact factor: 5.081

Review 3.  A risk-benefit assessment of pharmacological and nonpharmacological treatments for nausea and vomiting of pregnancy.

Authors:  P Mazzotta; L A Magee
Journal:  Drugs       Date:  2000-04       Impact factor: 9.546

Review 4.  Therapeutic potential of cannabinoids.

Authors:  D N Bateman; M D Rawlins
Journal:  Br Med J (Clin Res Ed)       Date:  1982-04-24

5.  Anticipatory nausea in animal models: a review of potential novel therapeutic treatments.

Authors:  Erin M Rock; Cheryl L Limebeer; Linda A Parker
Journal:  Exp Brain Res       Date:  2014-05-04       Impact factor: 1.972

6.  High-dose dexamethasone for prevention of cis-platin-induced vomiting.

Authors:  M S Aapro; D S Alberts
Journal:  Cancer Chemother Pharmacol       Date:  1981       Impact factor: 3.333

Review 7.  Nausea and vomiting associated with cancer chemotherapy: drug management in theory and in practice.

Authors:  E S Antonarakis; R D W Hain
Journal:  Arch Dis Child       Date:  2004-09       Impact factor: 3.791

Review 8.  The therapeutic potential of cannabis and cannabinoids.

Authors:  Franjo Grotenhermen; Kirsten Müller-Vahl
Journal:  Dtsch Arztebl Int       Date:  2012-07-23       Impact factor: 5.594

Review 9.  Pharmacokinetics of Cannabis in Cancer Cachexia-Anorexia Syndrome.

Authors:  Stephanie E Reuter; Jennifer H Martin
Journal:  Clin Pharmacokinet       Date:  2016-07       Impact factor: 6.447

Review 10.  Medical marijuana for digestive disorders: high time to prescribe?

Authors:  Mark E Gerich; Robert W Isfort; Bryan Brimhall; Corey A Siegel
Journal:  Am J Gastroenterol       Date:  2014-09-09       Impact factor: 10.864

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