Literature DB >> 6306454

Strand-break formation in DNA modified by benzo[alpha]pyrene diolepoxide. Quantitative cleavage by Escherichia coli uvrABC endonuclease.

E Seeberg, A L Steinum, M Nordenskjöld, S Söderhäll, B Jernström.   

Abstract

Covalently closed circular plasmid DNA was modified by benzo[alpha]pyrene diolepoxide and incubated with partially purified fractions of the Escherichia coli uvr+ gene products. Strand breaks were introduced into the modified DNA by the uvrABC endonuclease; on average, one break was formed for each bound benzo[alpha]pyrene residue in the DNA. These results are direct evidence that benzo[alpha]pyrene adducts in DNA are acted upon by the same repair enzyme as those that handle UV-induced lesions in DNA.

Entities:  

Mesh：

Substances：

Year:  1983        PMID： 6306454     DOI： 10.1016/0167-8817(83)90036-6

Source DB:  PubMed          Journal:  Mutat Res        ISSN： 0027-5107            Impact factor:   2.433


  9 in total

1.  ATPase activity of the UvrA and UvrAB protein complexes of the Escherichia coli UvrABC endonuclease.

Authors:  E Y Oh; L Claassen; S Thiagalingam; S Mazur; L Grossman
Journal:  Nucleic Acids Res       Date:  1989-06-12       Impact factor: 16.971

2.  The role of the excision-repair enzymes in mutation-induction by cis-Pt(NH3)2Cl2.

Authors:  J Brouwer; L Vollebregt; P van de Putte
Journal:  Nucleic Acids Res       Date:  1988-08-11       Impact factor: 16.971

3.  The effect of Escherichia coli Uvr protein binding on the topology of supercoiled DNA.

Authors:  E Y Oh; L Grossman
Journal:  Nucleic Acids Res       Date:  1986-11-11       Impact factor: 16.971

4.  A tale of two cities: A tribute to Aziz Sancar's Nobel Prize in Chemistry for his molecular characterization of NER.

Authors:  Bennett Van Houten
Journal:  DNA Repair (Amst)       Date:  2016-01

5.  Human genome-wide repair map of DNA damage caused by the cigarette smoke carcinogen benzo[a]pyrene.

Authors:  Wentao Li; Jinchuan Hu; Ogun Adebali; Sheera Adar; Yanyan Yang; Yi-Ying Chiou; Aziz Sancar
Journal:  Proc Natl Acad Sci U S A       Date:  2017-06-12       Impact factor: 11.205

Review 6.  Nucleotide excision repair in Escherichia coli.

Authors:  B Van Houten
Journal:  Microbiol Rev       Date:  1990-03

7.  Acetylaminofluorene bound to different guanines of the sequence -GGCGCC- is excised with different efficiencies by the UvrABC excision nuclease in a pattern not correlated to the potency of mutation induction.

Authors:  E Seeberg; R P Fuchs
Journal:  Proc Natl Acad Sci U S A       Date:  1990-01       Impact factor: 11.205

8.  Site-specific rates of excision repair of benzo[a]pyrene diol epoxide adducts in the hypoxanthine phosphoribosyltransferase gene of human fibroblasts: correlation with mutation spectra.

Authors:  D Wei; V M Maher; J J McCormick
Journal:  Proc Natl Acad Sci U S A       Date:  1995-03-14       Impact factor: 11.205

9.  pBR322 plasmid DNA modified with 2-acetylaminofluorene derivatives: transforming activity and in vitro strand cleavage by the Escherichia coli uvrABC endonuclease.

Authors:  R P Fuchs; E Seeberg
Journal:  EMBO J       Date:  1984-04       Impact factor: 11.598
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.