Literature DB >> 6303323

Demonstration of an S1-nuclease sensitive site near the human beta-globin gene, and its protection by HMG 1 and 2.

P N Cockerill, G H Goodwin.   

Abstract

An S1-nuclease sensitive site exists within supercoiled plasmids containing the 5'-flanking sequences of the human beta-globin gene. This site is located approximately 540 base pairs upstream from the start of the gene within a region of 52 alternating purine-pyrimidine residues which has the potential to adopt either cruciform structures or Z-form DNA. This site is protected from specific cleavage by S1-nuclease by the high-mobility-group chromosomal proteins HMG1 and 2, which may be specifically acting to protect short sequences of single-stranded DNA.

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Year:  1983        PMID： 6303323     DOI： 10.1016/0006-291x(83)91499-7

Source DB:  PubMed          Journal:  Biochem Biophys Res Commun        ISSN： 0006-291X            Impact factor:   3.575


  7 in total

1.  Phosphorylation of high mobility group 1 protein by phospholipid-sensitive Ca2+-dependent protein kinase from pig testis.

Authors:  K Kimura; N Katoh; K Sakurada; S Kubo
Journal:  Biochem J       Date:  1985-04-01       Impact factor: 3.857

2.  (A-T)n tracts embedded in random sequence DNA--formation of a structure which is chemically reactive and torsionally deformable.

Authors:  J A McClellan; E Palecek; D M Lilley
Journal:  Nucleic Acids Res       Date:  1986-12-09       Impact factor: 16.971

3.  Multiple sequence-specific DNA binding activities are eluted from chicken nuclei at low ionic strengths.

Authors:  M A Plumb; R H Nicolas; C A Wright; G H Goodwin
Journal:  Nucleic Acids Res       Date:  1985-06-11       Impact factor: 16.971

4.  Mung bean nuclease cleavage of a dA + dT-rich sequence or an inverted repeat sequence in supercoiled PM2 DNA depends on ionic environment.

Authors:  L G Sheflin; D Kowalski
Journal:  Nucleic Acids Res       Date:  1984-09-25       Impact factor: 16.971

Review 5.  HMGB1 in health and disease.

Authors:  Rui Kang; Ruochan Chen; Qiuhong Zhang; Wen Hou; Sha Wu; Lizhi Cao; Jin Huang; Yan Yu; Xue-Gong Fan; Zhengwen Yan; Xiaofang Sun; Haichao Wang; Qingde Wang; Allan Tsung; Timothy R Billiar; Herbert J Zeh; Michael T Lotze; Daolin Tang
Journal:  Mol Aspects Med       Date:  2014-07-08

6.  Human fetal globin DNA sequences suggest novel conversion event.

Authors:  C J Stoeckert; F S Collins; S M Weissman
Journal:  Nucleic Acids Res       Date:  1984-06-11       Impact factor: 16.971

7.  (AT)n is an interspersed repeat in the Xenopus genome.

Authors:  D R Greaves; R K Patient
Journal:  EMBO J       Date:  1985-10       Impact factor: 11.598
  7 in total

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