Literature DB >> 6300838

Isolation and preliminary characterization of the transforming gene of a human neuroblastoma cell line.

K Shimizu, M Goldfarb, M Perucho, M Wigler.   

Abstract

DNA from the human neuroblastoma cell line SK-N-SH is capable of inducing foci of transformed NIH 3T3 cells after DNA-mediated gene transfer. Using genetic selection with the Escherichia coli sup F gene, we have isolated human sequences from mouse cells responsible for the oncogenic transformation. These sequences are present in all human DNAs surveyed and no gross rearrangements of these sequences are found in SK-N-SH cells. Although clearly distinct from two other human transforming genes present in bladder, lung, and colon carcinoma cell lines, all three transforming gene sequences may be related members of the ras gene family.

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Year:  1983        PMID： 6300838      PMCID： PMC393381          DOI： 10.1073/pnas.80.2.383

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  30 in total

1.  Detection of specific sequences among DNA fragments separated by gel electrophoresis.

Authors:  E M Southern
Journal:  J Mol Biol       Date:  1975-11-05       Impact factor: 5.469

2.  A new technique for the assay of infectivity of human adenovirus 5 DNA.

Authors:  F L Graham; A J van der Eb
Journal:  Virology       Date:  1973-04       Impact factor: 3.616

3.  Construction of a colicin E1-R factor composite plasmid in vitro: means for amplification of deoxyribonucleic acid.

Authors:  T Tanaka; B Weisblum
Journal:  J Bacteriol       Date:  1975-01       Impact factor: 3.490

4.  Genetic and physical linkage of exogenous sequences in transformed cells.

Authors:  M Perucho; D Hanahan; M Wigler
Journal:  Cell       Date:  1980-11       Impact factor: 41.582

5.  Properties of a normal mouse cell DNA sequence (sarc) homologous to the src sequence of Moloney sarcoma virus.

Authors:  M Oskarsson; W L McClements; D G Blair; J V Maizel; G F Vande Woude
Journal:  Science       Date:  1980-03-14       Impact factor: 47.728

6.  Dual evolutionary origin for the rat genetic sequences of Harvey murine sarcoma virus.

Authors:  R W Ellis; D DeFeo; J M Maryak; H A Young; T Y Shih; E H Chang; D R Lowy; E M Scolnick
Journal:  J Virol       Date:  1980-11       Impact factor: 5.103

7.  Ubiquitous, interspersed repeated sequences in mammalian genomes.

Authors:  W R Jelinek; T P Toomey; L Leinwand; C H Duncan; P A Biro; P V Choudary; S M Weissman; C M Rubin; C M Houck; P L Deininger; C W Schmid
Journal:  Proc Natl Acad Sci U S A       Date:  1980-03       Impact factor: 11.205

8.  Murine sarcoma and leukemia viruses: assay using clonal lines of contact-inhibited mouse cells.

Authors:  J L Jainchill; S A Aaronson; G J Todaro
Journal:  J Virol       Date:  1969-11       Impact factor: 5.103

9.  Transforming genes of carcinomas and neuroblastomas introduced into mouse fibroblasts.

Authors:  C Shih; L C Padhy; M Murray; R A Weinberg
Journal:  Nature       Date:  1981-03-19       Impact factor: 49.962

10.  Nucleotide sequence of the rightward operator of phage lambda.

Authors:  T Maniatis; A Jeffrey; D G Kleid
Journal:  Proc Natl Acad Sci U S A       Date:  1975-03       Impact factor: 11.205
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  74 in total

1.  Characterization of four novel ras-like genes expressed in a human teratocarcinoma cell line.

Authors:  G T Drivas; A Shih; E Coutavas; M G Rush; P D'Eustachio
Journal:  Mol Cell Biol       Date:  1990-04       Impact factor: 4.272

2.  A polymorphic region defined by pCN2 (the 3' nontranslated region of N-ras) maps to chromosome 9cen-p12.

Authors:  T Nobori; L E Hexdall; D A Carson
Journal:  Hum Genet       Date:  1991-08       Impact factor: 4.132

Review 3.  Therapeutic targets for neuroblastomas.

Authors:  Garrett M Brodeur; Radhika Iyer; Jamie L Croucher; Tiangang Zhuang; Mayumi Higashi; Venkatadri Kolla
Journal:  Expert Opin Ther Targets       Date:  2014-01-06       Impact factor: 6.902

4.  Saccharomyces cerevisiae synthesizes proteins related to the p21 gene product of ras genes found in mammals.

Authors:  A G Papageorge; D Defeo-Jones; P Robinson; G Temeles; E M Scolnick
Journal:  Mol Cell Biol       Date:  1984-01       Impact factor: 4.272

Review 5.  Human oncogenes.

Authors:  K Willecke; R Schäfer
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

6.  Isolation of amplified DNA sequences from IMR-32 human neuroblastoma cells: facilitation by fluorescence-activated flow sorting of metaphase chromosomes.

Authors:  N Kanda; R Schreck; F Alt; G Bruns; D Baltimore; S Latt
Journal:  Proc Natl Acad Sci U S A       Date:  1983-07       Impact factor: 11.205

7.  Isolation and characterization of a stage-specific transforming gene, Tlym-I, from T-cell lymphomas.

Authors:  M A Lane; A Sainten; K M Doherty; G M Cooper
Journal:  Proc Natl Acad Sci U S A       Date:  1984-04       Impact factor: 11.205

8.  Glucocorticoids decrease c-fos expression in human nasal polyps in vivo.

Authors:  J N Baraniuk; G Wong; M Ali; M Sabol; T Troost
Journal:  Thorax       Date:  1998-07       Impact factor: 9.139

9.  Activated K-ras and N-ras oncogenes in primary renal mesenchymal tumors induced in F344 rats by methyl(methoxymethyl)nitrosamine.

Authors:  S Sukumar; A Perantoni; C Reed; J M Rice; M L Wenk
Journal:  Mol Cell Biol       Date:  1986-07       Impact factor: 4.272

Review 10.  Biology of tumors of the peripheral nervous system.

Authors:  G M Brodeur; J F Moley
Journal:  Cancer Metastasis Rev       Date:  1991-12       Impact factor: 9.264
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