Literature DB >> 6300095

The rat fibrinogen genes. Linkage of the A alpha and gamma chain genes.

J A Kant, G R Crabtree.   

Abstract

We have utilized cDNA probes for the alpha, beta, and gamma chains of rat fibrinogen to isolate the corresponding genes from two rat genomic libraries constructed in bacteriophage Charon 4A. There is a single copy of each gene. Mapping of greater than 92 kilobase pairs of rat genomic DNA has shown that the gamma and alpha chain genes are directly linked in a 5'-3' direction in vivo.

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Year:  1983        PMID： 6300095

Source DB:  PubMed          Journal:  J Biol Chem        ISSN： 0021-9258            Impact factor:   5.157


  10 in total

1.  Two variants of quantitative reverse transcriptase PCR used to show differential expression of alpha-, beta- and gamma-fibrinogen genes in rat liver lobes.

Authors:  J Zhang; M Desai; S E Ozanne; C Doherty; C N Hales; C D Byrne
Journal:  Biochem J       Date:  1997-02-01       Impact factor: 3.857

2.  The association of combined alpha and beta fibrinogen genotype on plasma fibrinogen levels in smokers and non-smokers.

Authors:  A E Thomas; F R Green; H Lamlum; S E Humphries
Journal:  J Med Genet       Date:  1995-08       Impact factor: 6.318

3.  The identification of a DNA polymorphism of the alpha fibrinogen gene, and the regional assignment of the human fibrinogen genes to 4q26-qter.

Authors:  S E Humphries; A M Imam; T P Robbins; M Cook; B Carritt; C Ingle; R Williamson
Journal:  Hum Genet       Date:  1984       Impact factor: 4.132

4.  Partial mRNA sequences for human A alpha, B beta, and gamma fibrinogen chains: evolutionary and functional implications.

Authors:  J A Kant; S T Lord; G R Crabtree
Journal:  Proc Natl Acad Sci U S A       Date:  1983-07       Impact factor: 11.205

5.  Evolution and organization of the fibrinogen locus on chromosome 4: gene duplication accompanied by transposition and inversion.

Authors:  J A Kant; A J Fornace; D Saxe; M I Simon; O W McBride; G R Crabtree
Journal:  Proc Natl Acad Sci U S A       Date:  1985-04       Impact factor: 11.205

6.  The genes coding for A alpha-, B beta-, and gamma-chains of fibrinogen map to 4q2.

Authors:  I Henry; G Uzan; D Weil; H Nicolas; J C Kaplan; C Marguerie; A Kahn; C Junien
Journal:  Am J Hum Genet       Date:  1984-07       Impact factor: 11.025

7.  Potential basis for regulation of the coordinately expressed fibrinogen genes: homology in the 5' flanking regions.

Authors:  D M Fowlkes; N T Mullis; C M Comeau; G R Crabtree
Journal:  Proc Natl Acad Sci U S A       Date:  1984-04       Impact factor: 11.205

8.  A 275 basepair fragment at the 5' end of the interleukin 2 gene enhances expression from a heterologous promoter in response to signals from the T cell antigen receptor.

Authors:  D B Durand; M R Bush; J G Morgan; A Weiss; G R Crabtree
Journal:  J Exp Med       Date:  1987-02-01       Impact factor: 14.307

9.  The coordinated regulation of fibrinogen gene transcription by hepatocyte-stimulating factor and dexamethasone.

Authors:  J M Otto; H E Grenett; G M Fuller
Journal:  J Cell Biol       Date:  1987-09       Impact factor: 10.539

10.  Trichomonas vaginalis is dependent on uptake and degradation of human low density lipoproteins.

Authors:  K M Peterson; J F Alderete
Journal:  J Exp Med       Date:  1984-11-01       Impact factor: 14.307
  10 in total

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