Literature DB >> 6299281

Activation of glycerophosphocholine phosphodiesterase in rat forebrain by Ca2+.

S Spanner, G B Ansell.   

Abstract

The highest activity of glycerophosphocholine phosphodiesterase (EC 3.1.4.2) in subcellular fractions of rat forebrain was found in the microsomal fraction though significant amounts were found in fractions containing plasma membranes. With the use of Ca(2+)/EGTA and Ca(2+)/EDTA buffers it was shown that very low concentrations of free Ca(2+) (EC(50)approx. 10(-9)m) could activate the enzyme.

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Year:  1982        PMID: 6299281      PMCID: PMC1154040          DOI: 10.1042/bj2080845

Source DB:  PubMed          Journal:  Biochem J        ISSN: 0264-6021            Impact factor:   3.857


  22 in total

1.  STUDIES OF GLYCERYLPHOSPHORYLCHOLINE DIESTERASE IN THE FEMALE REPRODUCTIVE TRACT.

Authors:  J C WALLACE; I G WHITE
Journal:  J Reprod Fertil       Date:  1965-04

2.  Glycerylphosphorylcholine diesterase activity of nervous tissue.

Authors:  G R WEBSTER; E A MARPLES; R H THOMPSON
Journal:  Biochem J       Date:  1957-02       Impact factor: 3.857

3.  Applications of metal buffers and metal indicators in biochemistry.

Authors:  J RAAFLAUB
Journal:  Methods Biochem Anal       Date:  1956

4.  The amounts of glycerylphosphorylcholine in some mammalian tissues.

Authors:  G SCHMIDT; L HECHT; P FALLOT; L GREENBAUM; S J THANNHAUSER
Journal:  J Biol Chem       Date:  1952-05       Impact factor: 5.157

5.  Protein measurement with the Folin phenol reagent.

Authors:  O H LOWRY; N J ROSEBROUGH; A L FARR; R J RANDALL
Journal:  J Biol Chem       Date:  1951-11       Impact factor: 5.157

6.  A calcium-activated polyphosphoinositide phosphodiesterase in the plasma membrane of human and rabbit erythrocytes.

Authors:  D Allan; R H Michell
Journal:  Biochim Biophys Acta       Date:  1978-04-04

7.  On the mechanism of activation of cyclic mucleotide phosphodiesterase by calmodulin.

Authors:  J H Wang; R K Sharma; C Y Huang; V Chau; P B Chock
Journal:  Ann N Y Acad Sci       Date:  1980       Impact factor: 5.691

8.  Choline kinase and ethanolamine kinase activity in the cytosol of nerve endings from rat forebrain.

Authors:  S Spanner; G B Ansell
Journal:  Biochem J       Date:  1979-03-15       Impact factor: 3.857

9.  The control by Ca2+ of the polyphosphoinositide phosphodiesterase and the Ca2+-pump ATPase in human erythrocytes.

Authors:  C P Downes; R H Michell
Journal:  Biochem J       Date:  1982-01-15       Impact factor: 3.857

10.  Choline and phospholipid metabolism and the synthesis of acetylcholine in rat brain.

Authors:  R S Jope; D J Jenden
Journal:  J Neurosci Res       Date:  1979       Impact factor: 4.164

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  9 in total

1.  The hydrolysis of glycerophosphocholine by rat brain microsomes: activation and inhibition.

Authors:  S Spanner; G B Ansell
Journal:  Neurochem Res       Date:  1987-02       Impact factor: 3.996

2.  Developmental and regional quantitation of glycerophosphorylcholine phosphodiesterase activities in rat brain.

Authors:  J N Kanfer; D G McCartney
Journal:  Neurochem Res       Date:  1988-09       Impact factor: 3.996

3.  Historical perspective: phosphatidylserine and phosphatidylethanolamine from the 1800s to the present.

Authors:  Jean E Vance
Journal:  J Lipid Res       Date:  2018-04-16       Impact factor: 5.922

4.  Characterization of glycerophosphocholine phosphodiesterase activity and phosphatidylcholine biosynthesis in cultured retinal microcapillary pericytes. Effect of adenosine and endothelin-1.

Authors:  Carmelina D Anfuso; Simonetta Sipione; Gabriella Lupo; Nicolò Ragusa; Mario Alberghina
Journal:  Lipids       Date:  2003-01       Impact factor: 1.880

5.  MIR16, a putative membrane glycerophosphodiester phosphodiesterase, interacts with RGS16.

Authors:  B Zheng; D Chen; M G Farquhar
Journal:  Proc Natl Acad Sci U S A       Date:  2000-04-11       Impact factor: 11.205

6.  Characterization of choline efflux from the perfused heart at rest and after muscarine receptor activation.

Authors:  R Lindmar; K Löffelholz; J Sandmann
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1986-03       Impact factor: 3.000

7.  Purification and properties of a glycerophosphocholine phosphodiesterase from bovine brain myelin.

Authors:  J Yuan; J N Kanfer
Journal:  Neurochem Res       Date:  1994-01       Impact factor: 3.996

8.  The release of choline from phospholipids mediated by beta-adrenoceptor activation in isolated hearts.

Authors:  R Lindmar; K Löffelholz; J Sandmann
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1986-11       Impact factor: 3.000

9.  Multiple forms of the enzyme glycerophosphodiesterase are present in human brain.

Authors:  B M Ross; A L Sherwin; S J Kish
Journal:  Lipids       Date:  1995-12       Impact factor: 1.880

  9 in total

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