Literature DB >> 629890

Simultaneous determination by gas chromatography of the major metabolites in urine of toluene, xylenes and styrene.

P B Van Roosmalen, I Drummond.   

Abstract

A gas chromatographic method has been developed to determine the following metabolites in urine simultaneously if necessary: hippuric acid from toluene or styrene; 3- and 4-methyl hippuric acids from xylenes; phenylglyoxylic acid and mandelic acid from styrene. Heptadecanoic acid is added to the urine as an internal standard and after ethyl acetate extraction from acidic solution, the trimethylsilyl (TMS) derivatives of the metabolites are formed and simultaneously analysed by gas chromatography on 3% OV-1 on 80/100 gas chrom Q (flame ionisation detector).

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Year:  1978        PMID： 629890      PMCID： PMC1008325          DOI： 10.1136/oem.35.1.56

Source DB:  PubMed          Journal:  Br J Ind Med        ISSN： 0007-1072


  12 in total

1.  Colorimetric method for hippuric acid.

Authors:  C J UMBERGER; F F FIORESE
Journal:  Clin Chem       Date:  1963-02       Impact factor: 8.327

2.  A fluorometric method for the determination of hippuric acid.

Authors:  G L ELLMAN; A BURKHALTER; J LADOU
Journal:  J Lab Clin Med       Date:  1961-05

3.  Measurement of toluene and xylene metabolites by gas chromatography.

Authors:  K Engström; K Husman; J Rantanen
Journal:  Int Arch Occup Environ Health       Date:  1976-01-26       Impact factor: 3.015

4.  A new gas chromatographic method for determination of mandelic acide in urine.

Authors:  K Engström; J Rantanen
Journal:  Int Arch Arbeitsmed       Date:  1974

5.  Measurement of urinary hippuric and m-methylhippuric acids by gas chromatography.

Authors:  J P Buchet; R R Lauwerys
Journal:  Br J Ind Med       Date:  1973-04

6.  A new method for determination of mandelic acid excretion at low level styrene exposure.

Authors:  A Slob
Journal:  Br J Ind Med       Date:  1973-10

7.  Urinary hippuric acid excretion as an index of toluene exposure.

Authors:  L D Pagnotto; L M Lieberman
Journal:  Am Ind Hyg Assoc J       Date:  1967 Mar-Apr

8.  Evaluation of hippuric, phenylglyoxylic and mandelic acids in urine as indices of styrene exposure.

Authors:  M Ikeda; T Imamura; M Hayaskh; T Tabuchi; I Hara
Journal:  Int Arch Arbeitsmed       Date:  1974

9.  The IARC program on the evaluation of the carcinogenic risk of chemicals to man.

Authors:  L Tomatis
Journal:  Ann N Y Acad Sci       Date:  1976       Impact factor: 5.691

10.  Quantitative determination in urine of hippuric acid and m- or p-methylhippuric acid, metabolites of toluene and m- or p-xylene.

Authors:  M Ogata; K Tomokuni; Y Takatsuka
Journal:  Br J Ind Med       Date:  1969-10
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  5 in total

1.  Urinary mandelic acid as an exposure test for ethylbenzene.

Authors:  J P Gromiec; J K Piotrowski
Journal:  Int Arch Occup Environ Health       Date:  1984       Impact factor: 3.015

2.  High-performance liquid chromatography for the quantitative determination of the urinary metabolites of toluene, xylene, and styrene.

Authors:  G Poggi; M Giusiani; U Palagi; P L Paggiaro; A M Loi; F Dazzi; C Siclari; L Baschieri
Journal:  Int Arch Occup Environ Health       Date:  1982       Impact factor: 3.015

3.  Simultaneous gas chromatographic determination of urinary mandelic and phenylglyoxylic acids using diazomethane derivatization.

Authors:  J Flek; V Sedivec
Journal:  Int Arch Occup Environ Health       Date:  1980-02       Impact factor: 3.015

4.  A new derivatization procedure for the analysis of hippuric acid and m-methyl-hippuric acid by gas chromatography.

Authors:  D de Carvalho; V L Lanchote; P S Bonato; R H Queiroz; A C Santos; S A Dreossi
Journal:  Int Arch Occup Environ Health       Date:  1991       Impact factor: 3.015

5.  The time course of mandelic and phenylglyoxylic acid excretion in workers exposed to styrene under model conditions.

Authors:  H K Wilson; J Cocker; C J Purnell; R H Brown; D Gompertz
Journal:  Br J Ind Med       Date:  1979-08
  5 in total

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