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Literature DB >> 6298714

Sequence organization of the ribosomal spacer of D.melanogaster.

A Simeone, A de Falco, G Macino, E Boncinelli.

Abstract

We subcloned several fragments of the rDNA nontranscribed spacer (NTS) of D.melanogaster and analysed their nucleotide sequence. The central portion contains a variable number of 240 base pair repeated sequences ending with two contiguous Alu I sites. Within every repeat there is a 42 base pair sequence perfectly homologous to the transcription initiation site from -18 to +24. Sequences homologous to the basic 240 bp repeat are present both at the end of the unique 1900 bp region downstream to the transcription termination site and within the unique region preceding the transcription initiation site up to nucleotide -140. These results are discussed in relation to the general problem of ribosomal gene units and their evolution.

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Year: 1982 PMID： 6298714 PMCID： PMC327083 DOI： 10.1093/nar/10.24.8263

Source DB: PubMed Journal: Nucleic Acids Res ISSN： 0305-1048 Impact factor: 16.971

31 in total

1. Restriction analysis of spacers in ribosomal DNA of Drosophila melanogaster.

Authors: E O Long; I B Dawid
Journal: Nucleic Acids Res Date: 1979-09-11 Impact factor: 16.971

Review 2. Eukaryotic RNA polymerases and the factors that control them.

Authors: B B Biswas; A Ganguly; A Das
Journal: Prog Nucleic Acid Res Mol Biol Date: 1975

3. Lengths and patterns of transcriptional units in the amplified nucleoli of oocytes of Xenopus laevis.

Authors: U Scheer; M F Trendelenburg; G Krohne; W W Franke
Journal: Chromosoma Date: 1977-03-16 Impact factor: 4.316

4. Transcription of spacer sequences in genes coding for ribosomal RNA in Xenopus cells.

Authors: D Rungger; H Achermann; M Crippa
Journal: Proc Natl Acad Sci U S A Date: 1979-08 Impact factor: 11.205

5. Amplification as a rectification mechanism for the redundant rRNA genes.

Authors: M Buongiorno-Nardelli; F Amaldi; P A Lava-Sanchez
Journal: Nat New Biol Date: 1972-08-02

6. Identification of the in vivo and in vitro origin of transcription in human rDNA.

Authors: R Miesfeld; N Arnheim
Journal: Nucleic Acids Res Date: 1982-07-10 Impact factor: 16.971

7. Circular ribosomal DNA during ribosomal magnification in Drosophila melanogaster.

Authors: F Graziani; R Caizzi; S Gargano
Journal: J Mol Biol Date: 1977-05-05 Impact factor: 5.469

8. The nucleotide sequence of the initiation and termination sites for ribosomal RNA transcription in X. laevis.

Authors: B Sollner-Webb; R H Reeder
Journal: Cell Date: 1979-10 Impact factor: 41.582

9. Processing steps and methylation in the formation of the ribosomal RNA of cultured Drosophila cells.

Authors: R Levis; S Penman
Journal: J Mol Biol Date: 1978-05-15 Impact factor: 5.469

10. Sequence organization of the spacer DNA in a ribosomal gene unit of Xenopus laevis.

Authors: P Boseley; T Moss; M Mächler; R Portmann; M Birnstiel
Journal: Cell Date: 1979-05 Impact factor: 41.582

20 in total

1. Chromosomal position effects reveal different cis-acting requirements for rDNA transcription and sex chromosome pairing in Drosophila melanogaster.

Authors: A Briscoe; J E Tomkiel
Journal: Genetics Date: 2000-07 Impact factor: 4.562

Sequence organization of the ribosomal spacer of D.melanogaster.

1. Restriction analysis of spacers in ribosomal DNA of Drosophila melanogaster.

Review 2. Eukaryotic RNA polymerases and the factors that control them.

3. Lengths and patterns of transcriptional units in the amplified nucleoli of oocytes of Xenopus laevis.

4. Transcription of spacer sequences in genes coding for ribosomal RNA in Xenopus cells.

5. Amplification as a rectification mechanism for the redundant rRNA genes.

6. Identification of the in vivo and in vitro origin of transcription in human rDNA.

7. Circular ribosomal DNA during ribosomal magnification in Drosophila melanogaster.

8. The nucleotide sequence of the initiation and termination sites for ribosomal RNA transcription in X. laevis.

9. Processing steps and methylation in the formation of the ribosomal RNA of cultured Drosophila cells.

10. Sequence organization of the spacer DNA in a ribosomal gene unit of Xenopus laevis.

1. Chromosomal position effects reveal different cis-acting requirements for rDNA transcription and sex chromosome pairing in Drosophila melanogaster.

2. Is higher-order structure conserved in eukaryotic ribosomal DNA intergenic spacers?

3. Transient expression of Drosophila melanogaster rDNA promoter into cultured Drosophila cells.

4. Differential magnification of rDNA gene types in bobbed mutants of Drosophila melanogaster.

5. Transcription of spacer sequences flanking the rat 45S ribosomal DNA gene.

6. Multiple repeated units in Drosophila melanogaster ribosomal DNA spacer stimulate rRNA precursor transcription.

7. Differential elimination of rDNA genes in bobbed mutants of Drosophila melanogaster.

8. Nucleotide sequence of a complete ribosomal spacer of D. melanogaster.

9. Transcription in cloned spacers of Xenopus laevis ribosomal DNA.

10. The origin of the rRNA precursor from Xenopus borealis, analysed in vivo and in vitro.