Literature DB >> 6297382

Synergism among BIOLF-62, phosphonoformate, and other antiherpetic compounds.

K O Smith, K S Galloway, K K Ogilvie, U O Cheriyan.   

Abstract

9-[[2-Hydroxy-1-(hydroxymethyl)ethoxy]methyl]guanine (BIOLF-62) is highly synergistic with either phosphonoformate or phosphonoacetate when used in combination against herpes simplex virus types 1 and 2 in vitro. Acycloguanosine did not show significant synergism with these two compounds. Bromovinyldeoxyuridine and phosphonoformate were highly synergistic against herpes simplex virus type 2, but not against type 1.

Entities:  

Mesh：

Substances：

Year:  1982        PMID： 6297382      PMCID： PMC185715          DOI： 10.1128/AAC.22.6.1026

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  25 in total

1.  Genital Herpesvirus homonis infection in mice. II. Treatment with phosphonoacetic acid, adenine arabinoside, and adenine arabinoside 5'-monophosphate.

Authors:  E R Kern; J T Richards; J C Overall; L A Glasgow
Journal:  J Infect Dis       Date:  1977-04       Impact factor: 5.226

2.  Selectivity of action of an antiherpetic agent, 9-(2-hydroxyethoxymethyl) guanine.

Authors:  G B Elion; P A Furman; J A Fyfe; P de Miranda; L Beauchamp; H J Schaeffer
Journal:  Proc Natl Acad Sci U S A       Date:  1977-12       Impact factor: 11.205

3.  Inhibition of herpesvirus replication and herpesvirus-induced deoxyribonucleic acid polymerase by phosphonoformate.

Authors:  J M Reno; L F Lee; J A Boezi
Journal:  Antimicrob Agents Chemother       Date:  1978-02       Impact factor: 5.191

4.  Comparative effectiveness of six antiviral agents in Herpes simplex type 1 infection of mice.

Authors:  E Lefkowitz; M Worthington; M A Conliffe; S Baron
Journal:  Proc Soc Exp Biol Med       Date:  1976-07

5.  Clinical evaluation of trifluorothymidine in the treatment of herpes simplex corneal ulcers.

Authors:  P C Wellings; P N Awdry; F H Bors; B R Jones; D C Brown; H E Kaufman
Journal:  Am J Ophthalmol       Date:  1972-06       Impact factor: 5.258

6.  Introductory remarks on adenine arabinoside.

Authors:  W M Shannon
Journal:  Ann N Y Acad Sci       Date:  1977-03-04       Impact factor: 5.691

7.  5-Nitro-2'-deoxyuridine and 5-nitro-2'-deoxyuridine 5'-monophosphate: antiviral activity and inhibition of thymidylate synthetase in vivo.

Authors:  E De Clercq; J Descamps; G F Huang; P F Torrence
Journal:  Mol Pharmacol       Date:  1978-05       Impact factor: 4.436

8.  Synergistic antiviral effects of adenine arabinoside and humoral antibodies in experimental encephalitis due to Herpesvirus hominis.

Authors:  C T Cho; K K Feng; N Brahmacupta
Journal:  J Infect Dis       Date:  1976-02       Impact factor: 5.226

9.  Suppression of herpes simplex virus infection by phosphonoacetic acid.

Authors:  N L Shipkowitz; R R Bower; R N Appell; C W Nordeen; L R Overby; W R Roderick; J B Schleicher; A M Von Esch
Journal:  Appl Microbiol       Date:  1973-09

10.  Differential sensitivity of herpes simplex virus types 1 and 2 to human interferon: antiviral effects of interferon plus 9-beta-D-arabinofuranosyladenine.

Authors:  A M Lerner; E J Bailey
Journal:  J Infect Dis       Date:  1976-10       Impact factor: 5.226
View more
  5 in total

1.  Mutually exclusive inhibition of herpesvirus DNA polymerase by aphidicolin, phosphonoformate, and acyclic nucleoside triphosphates.

Authors:  K B Frank; Y C Cheng
Journal:  Antimicrob Agents Chemother       Date:  1985-04       Impact factor: 5.191

Review 2.  Ganciclovir. A review of its antiviral activity, pharmacokinetic properties and therapeutic efficacy in cytomegalovirus infections.

Authors:  D Faulds; R C Heel
Journal:  Drugs       Date:  1990-04       Impact factor: 9.546

3.  Synergistic therapy by acyclovir and A1110U for mice orofacially infected with herpes simplex viruses.

Authors:  M N Ellis; D C Lobe; T Spector
Journal:  Antimicrob Agents Chemother       Date:  1989-10       Impact factor: 5.191

4.  Resistance of herpes simplex virus to 9-[[2-hydroxy-1-(hydroxymethyl)ethoxy]methyl]guanine: physical mapping of drug synergism within the viral DNA polymerase locus.

Authors:  C S Crumpacker; P N Kowalsky; S A Oliver; L E Schnipper; A K Field
Journal:  Proc Natl Acad Sci U S A       Date:  1984-03       Impact factor: 11.205

5.  Toxicity of intravitreal injection of foscarnet in the rabbit eye.

Authors:  S C She; G A Peyman; J A Schulman
Journal:  Int Ophthalmol       Date:  1988       Impact factor: 2.031
  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.