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Literature DB >> 6290958

Uracil synthesis via HCN oligomerization.

Abstract

Uracil is released from HCN oligomers upon acid hydrolysis in concentrations of 0.001% for 1 M HCN solutions to 0.005% for 0.1 M solutions. This yield is comparable with earlier reported, minor or nonbiological pyrimidines such as 5-hydroxyuracil and orotic acid. This is the first report of uracil itself via HCN oligomerization. Data are presented which establish that the observed uracil is not formed by decarboxylation of previously formed orotic acid, but via acid hydrolysis of at least two other precursors.

Entities: Chemical Gene

Mesh：

Substances：
Hydrogen Cyanide
Uracil

Year: 1982 PMID： 6290958 DOI： 10.1007/bf00926910

Source DB: PubMed Journal: Orig Life ISSN： 0302-1688

15 in total

1. Amino-acid synthesis from hydrogen cyanide under possible primitive earth conditions.

Authors: J ORO; S S KAMAT
Journal: Nature Date: 1961-04-29 Impact factor: 49.962

2. Chemical events on the primitive Earth.

Authors: P H Abelson
Journal: Proc Natl Acad Sci U S A Date: 1966-06 Impact factor: 11.205

3. Synthesis of uracil and thymine under simulated prebiotic conditions.

Authors: A W Schwartz; G J Chittenden
Journal: Biosystems Date: 1977-09 Impact factor: 1.973

4. Chemical evolution XXIX. Pyrimidines from hydrogen cyanide.

Authors: J P Ferris; P C Joshi; J G Lawless
Journal: Biosystems Date: 1977-09 Impact factor: 1.973

5. Chemical evolution. 18. Synthesis of pyrimidines from guanidine and cyanoacetaldehyde.

Authors: J P Ferris; O S Zamek; A M Altbuch; H Freiman
Journal: J Mol Evol Date: 1974 Impact factor: 2.395

6. Studies in prebiotic synthesis. II. Synthesis of purine precursors and amino acids from aqueous hydrogen cyanide.

Authors: R A Sanchez; J P Ferris; L E Orgel
Journal: J Mol Biol Date: 1967-12-14 Impact factor: 5.469

7. Chemical evolution. XXI. The amino acids released on hydrolysis of HCN oligomers.

Authors: J P Ferris; J D Wos; D W Nooner; J Oró
Journal: J Mol Evol Date: 1974 Impact factor: 2.395

8. Studies in prebiotic synthesis. 3. Synthesis of pyrimidines from cyanoacetylene and cyanate.

Authors: J P Ferris; R A Sanchez; L E Orgel
Journal: J Mol Biol Date: 1968-05-14 Impact factor: 5.469

9. Aminomalononitrile and 4-amino-5-cyanoimidazole in hydrogen cyanide polymerization and adenine synthesis.

Authors: J P Ferris; L E Orgel
Journal: J Am Chem Soc Date: 1965-11-05 Impact factor: 15.419

10. Synthesis of uracil under conditions of a thermal model of prebiological chemistry.

Authors: S W FOX; K HARADA
Journal: Science Date: 1961-06-16 Impact factor: 47.728

15 in total

1. The cold origin of life: B. Implications based on pyrimidines and purines produced from frozen ammonium cyanide solutions.

Authors: Shin Miyakawa; H James Cleaves; Stanley L Miller
Journal: Orig Life Evol Biosph Date: 2002-06 Impact factor: 1.950

2. Catalysis and prebiotic RNA synthesis.

Authors: J P Ferris
Journal: Orig Life Evol Biosph Date: 1993-12 Impact factor: 1.950

3. The effects of borate minerals on the synthesis of nucleic acid bases, amino acids and biogenic carboxylic acids from formamide.

Authors: Raffaele Saladino; Maurizio Barontini; Cristina Cossetti; Ernesto Di Mauro; Claudia Crestini
Journal: Orig Life Evol Biosph Date: 2011-03-19 Impact factor: 1.950

10. The effects of ferrous and other ions on the abiotic formation of biomolecules using aqueous aerosols and spark discharges.

Authors: M Ruiz-Bermejo; C Menor-Salván; S Osuna-Esteban; S Veintemillas-Verdaguer
Journal: Orig Life Evol Biosph Date: 2007-09-27 Impact factor: 1.950