| Literature DB >> 6289738 |
J G Spivack, W H Prusoff, T R Tritton.
Abstract
Methyl daunosamine inhibited the replication of herpes simplex virus type 1 in a dose-dependent manner. The growth of the host Vero cells was not affected by daunosamine levels that had significant antiviral activity (2.5 mM) but was inhibited by concentrations of 5 mM or greater. Methyl daunosamine appears to be unique among the sugars with antiviral activity because at antiviral concentrations it did not inhibit the glycosylation of macromolecules.Entities:
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Year: 1982 PMID: 6289738 PMCID: PMC183699 DOI: 10.1128/AAC.22.1.176
Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN: 0066-4804 Impact factor: 5.191