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Literature DB >> 6289737

Comparative in vitro activities of azlocillin-cefotaxime and azlocillin-tobramycin combinations against blood and multi-drug resistant bacterial isolates.

Abstract

The in vitro activities of azlocillin and cefotaxime in combination and of azlocillin and tobramycin in combination against 100 blood isolates and 50 multidrug-resistant isolates were compared. With both combinations, antibacterial spectrums were complementary. Although synergy against individual strains was infrequently observed (except for azlocillin-cefotaxime against Streptococcus faecalis and azlocillin-tobramycin against Pseudomonas aeruginosa), 97% of blood isolates and 76% of multidrug-resistant isolates were susceptible to azlocillin-cefotaxime, and 94% of blood isolates and 36% of multidrug-resistant isolates were susceptible to azlocyclin-tobramycin.

Entities: Chemical Species

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Year: 1982 PMID： 6289737 PMCID： PMC183696 DOI： 10.1128/AAC.22.1.167

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

11 in total

1. Analysis of the interactions between piperacillin, ticarcillin, or carbenicillin and aminoglycoside antibiotics.

Authors: P Chanbusarakum; P R Murray
Journal: Antimicrob Agents Chemother Date: 1978-09 Impact factor: 5.191

2. Carbenicillin plus cephalothin or cefazolin as therapy for infections in neutropenic patients.

Authors: G P Bodey; M Valdivieso; R Feld; V Rodriguez; K McCredie
Journal: Am J Med Sci Date: 1977 May-Jun Impact factor: 2.378

3. Antimicrobial activity of tobramycin and gentamicin used in combination with cephalothin and carbenicillin.

Authors: J Klastersky; A Henri; L Vandenborre
Journal: Am J Med Sci Date: 1973-07 Impact factor: 2.378

4. Comparative synergistic activity of cefoperazone, cefotaxime, moxalactam, and carbenicillin, combined with tobramycin, against Pseudomonas aeruginosa.

Authors: L Mintz; W L Drew
Journal: Antimicrob Agents Chemother Date: 1981-02 Impact factor: 5.191

5. In vitro activity of moxalactam and mecillinam, singly and in combination, against multi-drug-resistant Enterobacteriaceae and Pseudomonas species.

Authors: R J Fass
Journal: Antimicrob Agents Chemother Date: 1982-01 Impact factor: 5.191

6. Comparative in vitro synergistic activity of new beta-lactam antimicrobial agents and amikacin against Pseudomonas aeruginosa and Serratia marcescens.

Authors: T O Kurtz; D J Winston; D A Bruckner; W J Martin
Journal: Antimicrob Agents Chemother Date: 1981-08 Impact factor: 5.191

7. Comparative susceptibilities of clinical isolates of Serratia marcescens to newer cephalosporins, alone and in combination with various aminoglycosides.

Authors: S M Markowitz; D J Sibilla
Journal: Antimicrob Agents Chemother Date: 1980-11 Impact factor: 5.191

Review 8. In vitro susceptibilities of nonfermentative gram-negative bacilli other than Pseudomonas aeruginosa to 32 antimicrobial agents.

Authors: R J Fass; J Barnishan
Journal: Rev Infect Dis Date: 1980 Nov-Dec

9. In vitro activities of beta-lactam and aminoglycoside antibiotics. A comparative study of 20 parenterally administered drugs.

Authors: R J Fass
Journal: Arch Intern Med Date: 1980-06