| Literature DB >> 628842 |
K Javaherian, J F Liu, J C Wang.
Abstract
Two chromatin nonhistone proteins (from calf thymus) of the high mobility group, HMG1 and HMG2, reduce the linking number (topological winding number) of a circular DNA if the covalent closure of the DNA is carried out in their presence. This indicates that these proteins can either unwind the double helix, or induce a supercoiling of the DNA.Entities:
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Year: 1978 PMID： 628842 DOI： 10.1126/science.628842
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728