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Literature DB >> 6284647

Effect of lymphocytosis-promoting factor from Bordetella pertussis on cerebellar cyclic GMP levels.

Abstract

Dermonecrotic toxin (DNT), lipopolysaccharide (LPS), and lymphocytosis-promoting factor (LPF) were isolated from Bordetella pertussis and tested for neuroactivity. When injected intraperitoneally into rats, a dose of 0.13 mg of LPF per kg elevated the cyclic GMP level in cerebellum by approximately 70%, whereas DNT (0.5 mg/kg) and LPS (1.5 mg/kg) were without effect. This action of LPF on the central nervous system was dose dependent and did not require the administration of any additional agent, such as histamine.

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Year: 1982 PMID： 6284647 PMCID： PMC551423 DOI： 10.1128/iai.36.3.958-961.1982

Source DB: PubMed Journal: Infect Immun ISSN： 0019-9567 Impact factor: 3.441

23 in total

1. Histamine-sensitive adenylate cyclase in mammalian brain.

Authors: L R Hegstrand; P D Kanof; P Greengard
Journal: Nature Date: 1976-03-11 Impact factor: 49.962

2. A colorimetric method for the determination of sugars.

Authors: M DUBOIS; K GILLES; J K HAMILTON; P A REBERS; F SMITH
Journal: Nature Date: 1951-07-28 Impact factor: 49.962

3. Escherichia coli enterotoxin: stimulation of adenylate cyclase in broken-cell preparations.

Authors: F Dorner; P Mayer
Journal: Infect Immun Date: 1975-03 Impact factor: 3.441

4. Bicyclic phosphorus esters increase the cyclic GMP level in rat cerebellum.

Authors: H Mattsson; K Brandt; E Heilbronn
Journal: Nature Date: 1977-07-07 Impact factor: 49.962

Review 5. Evidence for involvement of GABA in the action of benzodiazepines: studies on rat cerebellum.

Authors: E Costa; A Guidotti; C C Mao
Journal: Adv Biochem Psychopharmacol Date: 1975

6. Heat-stable enterotoxin of Escherichia coli: in vitro effects on guanylate cyclase activity, cyclic GMP concentration, and ion transport in small intestine.

Authors: M Field; L H Graf; W J Laird; P L Smith
Journal: Proc Natl Acad Sci U S A Date: 1978-06 Impact factor: 11.205

7. Radioimmunoassay for cyclic nucleotides. II. Adenosine 3',5'-monophosphate and guanosine 3',5'-monophosphate in mammalian tissues and body fluids.

Authors: A L Steiner; A S Pagliara; L R Chase; D M Kipnis
Journal: J Biol Chem Date: 1972-02-25 Impact factor: 5.157

8. Transport of proteins across normal cerebral arterioles.

Authors: E Westergaard; M W Brightman
Journal: J Comp Neurol Date: 1973-11-01 Impact factor: 3.215

9. Purification and characterisation of a fimbrial haemagglutinin from Bordetella pertussis for use in an enzyme-linked immunosorbent assay.

Authors: P Askelöf; M Granström; P Gillenius; A A Lindberg
Journal: J Med Microbiol Date: 1982-02 Impact factor: 2.472

10. Bordetella pertussis respiratory tract infection in the mouse: pathophysiological responses.

Authors: M Pittman; B L Furman; A C Wardlaw
Journal: J Infect Dis Date: 1980-07 Impact factor: 5.226

5 in total

1. Engineering of genetically detoxified pertussis toxin analogs for development of a recombinant whooping cough vaccine.

Authors: S M Loosmore; G R Zealey; H A Boux; S A Cockle; K Radika; R E Fahim; G J Zobrist; R K Yacoob; P C Chong; F L Yao
Journal: Infect Immun Date: 1990-11 Impact factor: 3.441