Literature DB >> 6284244

Studies on some molecular properties of cytosol 5'-nucleotidase from rat liver.

R Itoh.   

Abstract

A cytosol 5'-nucleotidase was purified from rat liver. It appeared to be homogeneous on the criteria of polyacrylamide gel electrophoresis. We estimated the approximate molecular weight of the enzyme to be 200 000 and concluded that the enzyme most likely exists in the native state as a tetramer. Our results suggest that adenine nucleotides, which are activators of the enzyme, induce its conformational change.

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Year:  1982        PMID: 6284244     DOI: 10.1016/0304-4165(82)90208-2

Source DB:  PubMed          Journal:  Biochim Biophys Acta        ISSN: 0006-3002


  7 in total

1.  Inhibition of IMP-specific cytosolic 5'-nucleotidase and adenosine formation in rat polymorphonuclear leucocytes by 5'-deoxy-5'-isobutylthio derivatives of adenosine and inosine.

Authors:  A C Skladanowski; G B Sala; A C Newby
Journal:  Biochem J       Date:  1989-08-15       Impact factor: 3.857

2.  5-nucleotidase activity in cultured cell lines. Effect of different assay conditions and correlation with cell proliferation.

Authors:  J Turnay; N Olmo; G Risse; K von der Mark; M A Lizarbe
Journal:  In Vitro Cell Dev Biol       Date:  1989-11

3.  5'-Nucleotidases in rat heart. Evidence for the occurrence of two soluble enzymes with different substrate specificities.

Authors:  V L Truong; A R Collinson; J M Lowenstein
Journal:  Biochem J       Date:  1988-07-01       Impact factor: 3.857

4.  Partial purification and properties of an AMP-specific soluble 5'-nucleotidase from pigeon heart.

Authors:  A C Skladanowski; A C Newby
Journal:  Biochem J       Date:  1990-05-15       Impact factor: 3.857

5.  5'-Nucleotidase activities in human erythrocytes. Identification of a purine 5'-nucleotidase stimulated by ATP and glycerate 2,3-bisphosphate.

Authors:  F Bontemps; G Van den Berghe; H G Hers
Journal:  Biochem J       Date:  1988-03-15       Impact factor: 3.857

6.  The mechanism of adenosine production in rat polymorphonuclear leucocytes.

Authors:  Y Worku; A C Newby
Journal:  Biochem J       Date:  1983-08-15       Impact factor: 3.857

7.  Oligomeric interface modulation causes misregulation of purine 5´-nucleotidase in relapsed leukemia.

Authors:  Aleš Hnízda; Jana Škerlová; Milan Fábry; Petr Pachl; Martina Šinalová; Lukáš Vrzal; Petr Man; Petr Novák; Pavlína Řezáčová; Václav Veverka
Journal:  BMC Biol       Date:  2016-10-19       Impact factor: 7.431

  7 in total

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