Literature DB >> 6277302

Acetoacetate is an electron donor to myeloperoxidase and a promoter of myeloperoxidase-catalyzed fatty acid peroxidation.

J E Harrison, F A Saeed.   

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Year:  1981        PMID: 6277302     DOI: 10.1016/0006-2944(81)90010-7

Source DB:  PubMed          Journal:  Biochem Med        ISSN: 0006-2944


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  6 in total

1.  Neutrophil chemiluminescence during phagocytosis is inhibited by abnormally elevated levels of acetoacetate: implications for diabetic susceptibility to infections.

Authors:  F A Saeed; G E Castle
Journal:  Clin Diagn Lab Immunol       Date:  1998-09

2.  Myoglobin-H2O2 catalyzes the oxidation of β-ketoacids to α-dicarbonyls: mechanism and implications in ketosis.

Authors:  Douglas Ganini; Marcelo Christoff; Marilyn Ehrenshaft; Maria B Kadiiska; Ronald P Mason; Etelvino J H Bechara
Journal:  Free Radic Biol Med       Date:  2011-05-08       Impact factor: 7.376

3.  Decreased cystathionine-γ-lyase (CSE) activity in livers of type 1 diabetic rats and peripheral blood mononuclear cells (PBMC) of type 1 diabetic patients.

Authors:  Prasenjit Manna; Neslihan Gungor; Robert McVie; Sushil K Jain
Journal:  J Biol Chem       Date:  2014-03-07       Impact factor: 5.157

4.  Hyperketonemia (acetoacetate) upregulates NADPH oxidase 4 and elevates oxidative stress, ICAM-1, and monocyte adhesivity in endothelial cells.

Authors:  Preeti Kanikarla-Marie; Sushil K Jain
Journal:  Cell Physiol Biochem       Date:  2015-01-13

5.  1,25(OH)2D3 inhibits oxidative stress and monocyte adhesion by mediating the upregulation of GCLC and GSH in endothelial cells treated with acetoacetate (ketosis).

Authors:  Preeti Kanikarla-Marie; Sushil K Jain
Journal:  J Steroid Biochem Mol Biol       Date:  2016-03-03       Impact factor: 4.292

Review 6.  Hyperketonemia and ketosis increase the risk of complications in type 1 diabetes.

Authors:  Preeti Kanikarla-Marie; Sushil K Jain
Journal:  Free Radic Biol Med       Date:  2016-03-29       Impact factor: 7.376

  6 in total

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