Literature DB >> 6275277

AQA 39*, a new bradycardic agent which blocks myocardial calcium (Ca) channels in a frequency- and voltage-dependent manner.

W Trautwein, D Pelzer, T F McDonald, W Osterrieder.   

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Year:  1981        PMID: 6275277     DOI: 10.1007/bf00503822

Source DB:  PubMed          Journal:  Naunyn Schmiedebergs Arch Pharmacol        ISSN: 0028-1298            Impact factor:   3.000


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  12 in total

1.  Inotropic and electrophysiological actions of verapamil and D 600 in mammalian myocardium. III. Effects of the optical isomers on transmembrane action potentials.

Authors:  R Bayer; D Kalusche; R Kaufmann; R Mannhold
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1975       Impact factor: 3.000

2.  Calcium conductance and tension in mammalian ventricular muscle.

Authors:  W Trautwein; T F McDonald; O Tripathi
Journal:  Pflugers Arch       Date:  1975       Impact factor: 3.657

3.  Membrane currents underlying activity in frog sinus venosus.

Authors:  H F Brown; W Giles; S J Noble
Journal:  J Physiol       Date:  1977-10       Impact factor: 5.182

4.  Inward membrane currents in mammalian myocardium.

Authors:  W New; W Trautwein
Journal:  Pflugers Arch       Date:  1972       Impact factor: 3.657

5.  The electrophysiological basis of the bradycardic action of AQA 39 on the sinoatrial node.

Authors:  W Osterrieder; D Pelzer; Q F Yang; W Trautwein
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1981-11       Impact factor: 3.000

6.  Membrane currents in cat myocardium: separation of inward and outward components.

Authors:  T F McDonald; W Trautwein
Journal:  J Physiol       Date:  1978-01       Impact factor: 5.182

7.  The voltage- and time-dependent effects of (-)-verapamil on the slow inward current in isolated cat ventricular myocardium.

Authors:  T Ehara; R Daufmann
Journal:  J Pharmacol Exp Ther       Date:  1978-10       Impact factor: 4.030

8.  On the mechanism of slow calcium channel block in heart.

Authors:  T F McDonald; D Pelzer; W Trautwein
Journal:  Pflugers Arch       Date:  1980-05       Impact factor: 3.657

9.  Inotropic and electrophysiological actions of verapamil and D 600 in mammalian myocardium. I. Pattern of inotropic effects of the racemic compounds.

Authors:  R Bayer; R Hennekes; R Kaufmann; R Mannhold
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1975       Impact factor: 3.000

10.  On the mechanism underlying the action of D-600 on slow inward current and tension in mammalian myocardium.

Authors:  H Nawrath; R E Eick; T F McDonald; W Trautwein
Journal:  Circ Res       Date:  1977-04       Impact factor: 17.367

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  9 in total

1.  Cat ventricular muscle treated with D600: characteristics of calcium channel block and unblock.

Authors:  T F McDonald; D Pelzer; W Trautwein
Journal:  J Physiol       Date:  1984-07       Impact factor: 5.182

2.  The electrophysiological basis of the bradycardic action of AQA 39 on the sinoatrial node.

Authors:  W Osterrieder; D Pelzer; Q F Yang; W Trautwein
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1981-11       Impact factor: 3.000

3.  Calcium channel block and recovery from block in mammalian ventricular muscle treated with organic channel inhibitors.

Authors:  D Pelzer; W Trautwein; T F McDonald
Journal:  Pflugers Arch       Date:  1982-08       Impact factor: 3.657

4.  On the mechanism of the "specific bradycardic action" of the verapamil derivative UL-FS 49.

Authors:  T Doerr; W Trautwein
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1990-04       Impact factor: 3.000

5.  Does the organic calcium channel blocker D600 act from inside or outside on the cardiac cell membrane?

Authors:  J Hescheler; D Pelzer; G Trube; W Trautwein
Journal:  Pflugers Arch       Date:  1982-06       Impact factor: 3.657

6.  Inhibition of potassium outward currents and pacemaker current in sheep cardiac Purkinje fibres by the verapamil derivative YS 035.

Authors:  F Berger; U Borchard; D Hafner; T Kammer; T Weis
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1991-12       Impact factor: 3.000

7.  Effects of propafenone on calcium current in guinea-pig ventricular myocytes.

Authors:  C Delgado; J Tamargo; D Henzel; P Lorente
Journal:  Br J Pharmacol       Date:  1993-03       Impact factor: 8.739

Review 8.  Channel-mediated calcium current in the heart.

Authors:  W A Coetzee
Journal:  Cardiovasc Drugs Ther       Date:  1988-01       Impact factor: 3.727

9.  Inhibition of the myocardial Ca2+ inward current by the class 1 antiarrhythmic agent, cibenzoline.

Authors:  M Holck; W Osterrieder
Journal:  Br J Pharmacol       Date:  1986-04       Impact factor: 8.739

  9 in total

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