| Literature DB >> 6274020 |
D A Peterson, J M Gerrard, S M Glover, G H Rao, J G White.
Abstract
Alpha-adrenergic agonists that promote platelet aggregation were found to reduce ferric heme to ferrous heme. Agents that bind iron in heme inhibited epinephrine-induced platelet aggregation. It is proposed that epinephrine first binds to its receptor and then reduces an adjacent heme group to transmit its agonist stimulus.Entities:
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Year: 1982 PMID： 6274020 DOI： 10.1126/science.6274020
Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728