Literature DB >> 11383698

Triple-bonded unsaturated fatty acids are redox active compounds.

D A Peterson1, H L Reeve, D Nelson, S L Archer, E K Weir.   

Abstract

Unsaturated fatty acids with triple bonds are used as inhibitors of unsaturated fatty acid metabolism or cytochrome P450 reactions because they are believed to be chemically inert. In this paper we use in vitro cytochrome C reduction to show that two commonly used triple-bonded unsaturated fatty acids are in fact potent electron transfer agents and could affect the multiple cellular systems that are redox-modulated.

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Year:  2001        PMID： 11383698     DOI： 10.1007/s11745-001-0740-6

Source DB:  PubMed          Journal:  Lipids        ISSN： 0024-4201            Impact factor:   1.880


  21 in total

1.  Evidence for a novel thioredoxin-like catalytic property of gonadotropic hormones.

Authors:  J J Boniface; L E Reichert
Journal:  Science       Date:  1990-01-05       Impact factor: 47.728

2.  Rates of DNA-mediated electron transfer between metallointercalators.

Authors:  M R Arkin; E D Stemp; R E Holmlin; J K Barton; A Hörmann; E J Olson; P F Barbara
Journal:  Science       Date:  1996-07-26       Impact factor: 47.728

3.  Dihydropyridine Ca2+ agonists and channel blockers interact in the opposite manner with photogenerated unpaired electrons.

Authors:  B S Marinov; M E Saxon
Journal:  FEBS Lett       Date:  1985-07-08       Impact factor: 4.124

4.  The dopaminergic D receptor: another example of reductive activation?

Authors:  D A Peterson; J Butterfield; J M Garrard
Journal:  Med Hypotheses       Date:  1988-05       Impact factor: 1.538

5.  Sulfhydryl oxidation induces rapid and reversible closure of the ATP-regulated K+ channel in the pancreatic beta-cell.

Authors:  M S Islam; P O Berggren; O Larsson
Journal:  FEBS Lett       Date:  1993-03-15       Impact factor: 4.124

6.  Cyclic oxidation-reduction reactions regulate thromboxane A2/prostaglandin H2 receptor number and affinity in human platelet membranes.

Authors:  G W Dorn
Journal:  J Biol Chem       Date:  1990-03-15       Impact factor: 5.157

7.  A hypothesis for a role for unsaturated fatty acids in electron transport and its potential application to understanding the mitochondrial respiratory chain.

Authors:  D A Peterson; J M Gerrard
Journal:  Med Hypotheses       Date:  1980-05       Impact factor: 1.538

8.  Prostaglandins as reducing agents: a model of adenylate cyclase activation?

Authors:  D A Peterson; B Kelly; N Mehta; J M Gerrard
Journal:  Prostaglandins       Date:  1988-11

9.  Epinephrine reduction of heme: implication for understanding the transmission of an agonist stimulus.

Authors:  D A Peterson; J M Gerrard; S M Glover; G H Rao; J G White
Journal:  Science       Date:  1982-01-01       Impact factor: 47.728

10.  Free, long-chain, polyunsaturated fatty acids reduce membrane electrical excitability in neonatal rat cardiac myocytes.

Authors:  J X Kang; Y F Xiao; A Leaf
Journal:  Proc Natl Acad Sci U S A       Date:  1995-04-25       Impact factor: 11.205
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