Literature DB >> 6273870

Single channel currents induced by complement in antibody-coated cell membranes.

M B Jackson, C L Stephens, H Lecar.   

Abstract

An extracellular patch electrode was used to record ionic currents from individual complement-induced channels in the membranes of antibody-coated skeletal muscle. The amplitude of the single-channel currents leads to an estimate of 90 pS for the unit conductance. The kinetics of channel opening and closing show marked variability and complexity. Channels flicker open and closed repeatedly, indicating that once these lesions form, they undergo rapid structural transitions between discrete conducting and nonconducting states.

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Year:  1981        PMID: 6273870      PMCID: PMC349051          DOI: 10.1073/pnas.78.10.6421

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN: 0027-8424            Impact factor:   11.205


  27 in total

1.  Single-channel currents recorded from membrane of denervated frog muscle fibres.

Authors:  E Neher; B Sakmann
Journal:  Nature       Date:  1976-04-29       Impact factor: 49.962

2.  Shot noise in ion channels.

Authors:  P Läuger
Journal:  Biochim Biophys Acta       Date:  1975-11-17

3.  Step conductance increases in bilayer membranes induced by antibody-antigen-complement action.

Authors:  D Wobschall; C McKeon
Journal:  Biochim Biophys Acta       Date:  1975-12-01

4.  The nature of the voltage-dependent conductance of the hemocyanin channel.

Authors:  R Latorre; O Alvarez; G Ehrenstein; M Espinoza; J Reyes
Journal:  J Membr Biol       Date:  1975-12-04       Impact factor: 1.843

Review 5.  The lesions in cell membranes caused by complement.

Authors:  J H Humphrey; R R Dourmashkin
Journal:  Adv Immunol       Date:  1969       Impact factor: 3.543

6.  Studies of guinea pig complement component C9: reaction kinetics and evidence that lysis of EAC1-8 results from a single membrane lesion caused by one molecule of C9.

Authors:  F A Rommel; M M Mayer
Journal:  J Immunol       Date:  1973-03       Impact factor: 5.422

7.  Resistance changes in lipid bilayers: immunological applications.

Authors:  P Barfort; E R Arquilla; P O Vogelhut
Journal:  Science       Date:  1968-06-07       Impact factor: 47.728

8.  Is the primary complement lesion insufficient for lysis? Failure of cells damaged under osmotic protection to lyse in EDTA or at low temperature after removal of osmotic protection.

Authors:  S J Burakoff; E Martz; B Benacerraf
Journal:  Clin Immunol Immunopathol       Date:  1975-05

9.  Lipid films as transducers for detection of antigen-antibody and enzyme-substrate reactions.

Authors:  J Del Castillo; A Rodriguez; C A Romero; V Sanchez
Journal:  Science       Date:  1966-07-08       Impact factor: 47.728

10.  Effect of antibody and complement on permeability control in ascites tumor cells and erythrocytes.

Authors:  H GREEN; P BARROW; B GOLDBERG
Journal:  J Exp Med       Date:  1959-11-01       Impact factor: 14.307

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  13 in total

1.  Pore formation by complement in the outer membrane of gram-negative bacteria studied with asymmetric planar lipopolysaccharide/phospholipid bilayers.

Authors:  G Schröder; K Brandenburg; L Brade; U Seydel
Journal:  J Membr Biol       Date:  1990-11       Impact factor: 1.843

2.  Complement pore genesis observed in erythrocyte membranes by fluorescence microscopic single-channel recording.

Authors:  H Sauer; L Pratsch; G Fritzsch; S Bhakdi; R Peters
Journal:  Biochem J       Date:  1991-06-01       Impact factor: 3.857

3.  Formation of ion-conducting channels by the membrane attack complex proteins of complement.

Authors:  J W Shiver; J R Dankert; A F Esser
Journal:  Biophys J       Date:  1991-10       Impact factor: 4.033

4.  Immunoglobulin G-induced single ionic channels in human alveolar macrophage membranes.

Authors:  D J Nelson; E R Jacobs; J M Tang; J M Zeller; R C Bone
Journal:  J Clin Invest       Date:  1985-08       Impact factor: 14.808

5.  Single-channel analysis of the conductance fluctuations induced in lipid bilayer membranes by complement proteins C5b-9.

Authors:  R Benz; A Schmid; T Wiedmer; P J Sims
Journal:  J Membr Biol       Date:  1986       Impact factor: 1.843

6.  Non-lethal complement-membrane attack on human neutrophils: transient cell swelling and metabolic depletion.

Authors:  B P Morgan
Journal:  Immunology       Date:  1988-01       Impact factor: 7.397

7.  Sublytic membrane-attack-complex (MAC) activation alters regulated rather than constitutive vascular endothelial growth factor (VEGF) secretion in retinal pigment epithelium monolayers.

Authors:  Kannan Kunchithapautham; Bärbel Rohrer
Journal:  J Biol Chem       Date:  2011-05-12       Impact factor: 5.157

Review 8.  Complement membrane attack on nucleated cells: resistance, recovery and non-lethal effects.

Authors:  B P Morgan
Journal:  Biochem J       Date:  1989-11-15       Impact factor: 3.857

9.  Localization of 20-kD homologous restriction factor (HRF20) in diseased human glomeruli. An immunofluorescence study.

Authors:  H Tamai; S Matsuo; A Fukatsu; K Nishikawa; N Sakamoto; K Yoshioka; N Okada; H Okada
Journal:  Clin Exp Immunol       Date:  1991-05       Impact factor: 4.330

10.  Formation of complement membrane attack complex in mammalian cerebral cortex evokes seizures and neurodegeneration.

Authors:  Zhi-Qi Xiong; Weihua Qian; Katsuaki Suzuki; James O McNamara
Journal:  J Neurosci       Date:  2003-02-01       Impact factor: 6.167

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