Literature DB >> 6273185

Peripheral benzodiazepine binding sites in heart and their interaction with dipyridamole.

L P Davies, V Huston.   

Abstract

Specific binding of [3H]diazepam to rat and guinea-pig heart tissue has been found. These binding sites are similar to those in lung, liver, kidney and mast cells but differ from those in the brain. Dipyridamole interacts with this receptor and is several fold more potent as a displacer of [3H]diazepam bound to heart preparations than to brain membranes. Specific binding per unit protein in the left ventricle, right ventricle and interventricular septum is significantly higher than in the left and right atrium.

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Year:  1981        PMID： 6273185     DOI： 10.1016/0014-2999(81)90092-3

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  17 in total

1.  The development of mitochondrial membrane affinity chromatography columns for the study of mitochondrial transmembrane proteins.

Authors:  K-L Habicht; N S Singh; F E Indig; I W Wainer; R Moaddel; R Shimmo
Journal:  Anal Biochem       Date:  2015-06-04       Impact factor: 3.365

2.  Putative diazepam binding inhibitor peptide: cDNA clones from rat.

Authors:  I Mocchetti; R Einstein; J Brosius
Journal:  Proc Natl Acad Sci U S A       Date:  1986-10       Impact factor: 11.205

3.  Tissue-specific alterations of binding sites for peripheral-type benzodiazepine receptor ligand [3H]PK11195 in rats following portacaval anastomosis.

Authors:  V L Rao; R Audet; G Therrien; R F Butterworth
Journal:  Dig Dis Sci       Date:  1994-05       Impact factor: 3.199

4.  Enhancement by benzodiazepines of the inhibitory effect of adenosine on skeletal neuromuscular transmission.

Authors:  L C Chiou; J Y Ling; C C Chang
Journal:  Br J Pharmacol       Date:  1995-09       Impact factor: 8.739

5.  Peripheral benzodiazepine receptor/translocator protein global knock-out mice are viable with no effects on steroid hormone biosynthesis.

Authors:  Lan N Tu; Kanako Morohaku; Pulak R Manna; Susanne H Pelton; W Ronald Butler; Douglas M Stocco; Vimal Selvaraj
Journal:  J Biol Chem       Date:  2014-06-16       Impact factor: 5.157

6.  Benzodiazepines that bind at peripheral sites inhibit cell proliferation.

Authors:  J K Wang; J I Morgan; S Spector
Journal:  Proc Natl Acad Sci U S A       Date:  1984-02       Impact factor: 11.205

7.  Interaction of calcium channel blockers with non-neuronal benzodiazepine binding sites.

Authors:  E H Cantor; A Kenessey; G Semenuk; S Spector
Journal:  Proc Natl Acad Sci U S A       Date:  1984-03       Impact factor: 11.205

8.  Differential effects of anxiogenic central and peripheral benzodiazepine receptor ligands in tests of learning and memory.

Authors:  P V Holmes; R C Drugan
Journal:  Psychopharmacology (Berl)       Date:  1991       Impact factor: 4.530

9.  Differentiation of Friend erythroleukemia cells induced by benzodiazepines.

Authors:  J K Wang; J I Morgan; S Spector
Journal:  Proc Natl Acad Sci U S A       Date:  1984-06       Impact factor: 11.205

10.  The effect of RO15-1788 on cardiovascular depression caused by fentanyl and diazepam.

Authors:  T Sone; T Kato; I Tsukahara; T Harada; M Yamamoto; A Talbot
Journal:  J Anesth       Date:  1988-03-01       Impact factor: 2.078
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