Literature DB >> 6272984

In vitro metabolism of acrylonitrile to 2-cyanoethylene oxide, reaction with glutathione, and irreversible binding to proteins and nucleic acids.

F P Guengerich, L E Geiger, L L Hogy, P L Wright.   

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Year:  1981        PMID： 6272984

Source DB:  PubMed          Journal:  Cancer Res        ISSN： 0008-5472            Impact factor:   12.701


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  17 in total

1.  Toxicity of acrylonitrile in a human neuroblastoma cell line and its effect on glutathione and glutathione-S-transferase.

Authors:  D Cova; P Fumagalli; A Santagostino
Journal:  Bull Environ Contam Toxicol       Date:  1992-12       Impact factor: 2.151

2.  Site specific synthesis and polymerase bypass of oligonucleotides containing a 6-hydroxy-3,5,6,7-tetrahydro-9H-imidazo[1,2-a]purin-9-one base, an intermediate in the formation of 1,N2-etheno-2'-deoxyguanosine.

Authors:  Angela K Goodenough; Ivan D Kozekov; Hong Zang; Jeong-Yun Choi; F Peter Guengerich; Thomas M Harris; Carmelo J Rizzo
Journal:  Chem Res Toxicol       Date:  2005-11       Impact factor: 3.739

3.  Differential response to acrylonitrile toxicity in rat primary astrocytes and microglia.

Authors:  Samuel Caito; Yingchun Yu; Michael Aschner
Journal:  Neurotoxicology       Date:  2013-04-26       Impact factor: 4.294

4.  N-acetyl-S-(1-cyano-2-hydroxyethyl)-L-cysteine, a new urinary metabolite of acrylonitrile and oxiranecarbonitrile.

Authors:  I Linhart; J Smejkal; J Novák
Journal:  Arch Toxicol       Date:  1988       Impact factor: 5.153

5.  Modulation of acrylonitrile-induced embryotoxicity in vitro by glutathione depletion.

Authors:  A M Saillenfait; J P Payan; I Langonné; D Beydon; M C Grandclaude; J P Sabaté; J de Ceaurriz
Journal:  Arch Toxicol       Date:  1993       Impact factor: 5.153

6.  Automated computational screening of the thiol reactivity of substituted alkenes.

Authors:  Jennifer M Smith; Christopher N Rowley
Journal:  J Comput Aided Mol Des       Date:  2015-07-10       Impact factor: 3.686

7.  Biological monitoring of acrylonitrile exposure through a new analytical approach to hemoglobin and plasma protein adducts and urinary metabolites in rats and humans.

Authors:  V Ivanov; K Hashimoto; K Inomata; T Kawai; K Mizunuma; L Klimatskaya
Journal:  Int Arch Occup Environ Health       Date:  1993       Impact factor: 3.015

8.  Kinetic and equilibrium studies of acrylonitrile binding to cytochrome c peroxidase and oxidation of acrylonitrile by cytochrome c peroxidase compound I.

Authors:  Diana Chinchilla; Heather Kilheeney; Lidia B Vitello; James E Erman
Journal:  Biochem Biophys Res Commun       Date:  2013-11-28       Impact factor: 3.575

9.  Comparative metabolism and disposition of acrylonitrile and methacrylonitrile in rats.

Authors:  L T Burka; I M Sanchez; A E Ahmed; B I Ghanayem
Journal:  Arch Toxicol       Date:  1994       Impact factor: 5.153

10.  Urinary excretion of acrylonitrile and its metabolites in rats.

Authors:  G Müller; C Verkoyen; N Soton; K Norpoth
Journal:  Arch Toxicol       Date:  1987-08       Impact factor: 5.153
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