Literature DB >> 6272321

Pleiotropic expression of Epstein--Barr virus DNA in human epithelial cells.

J Stoerker, D Parris, Y Yajima, R Glaser.   

Abstract

We have attempted to establish a system that can be used to study the association of Epstein--Barr virus (EBV) with epithelial cells. Attempts were made to transfect human carcinoma cells with EBV DNA. Successful transfection was confirmed by the expression of EBV-specific early antigen (EA), virus capsid antigen, and the presence of virus DNA. The transfecting preparation contained a mixture of EBV and cellular DNA extracted from two producer cell lines, P3HR-1 and AG-876. Our data suggest that virus DNA obtained from the P3HR-1 nontransforming, EA-inducing strain of EBV was lytically expressed in the epithelial tumor cells. The DNA derived from AG-876 cells, which produce a transforming, non-EA-inducing strain of EBV, also produced a lytic infection.

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Year:  1981        PMID： 6272321      PMCID： PMC348885          DOI： 10.1073/pnas.78.9.5852

Source DB:  PubMed          Journal:  Proc Natl Acad Sci U S A        ISSN： 0027-8424            Impact factor:   11.205


  20 in total

1.  Antibodies to Epstein-Barr virus in nasopharyngeal carcinoma, other head and neck neoplasms, and control groups.

Authors:  W Henle; G Henle; H C Ho; P Burtin; Y Cachin; P Clifford; A de Schryver; G de-Thé; V Diehl; G Klein
Journal:  J Natl Cancer Inst       Date:  1970-01       Impact factor: 13.506

2.  Transfection of human lymphoblastoid cells with herpes simplex viral DNA.

Authors:  G Miller; P Wertheim; G Wilson; J Robinson; J L Geelen; J van der Noordaa; A J van der Eb
Journal:  Proc Natl Acad Sci U S A       Date:  1979-02       Impact factor: 11.205

3.  Precipitating antibody in human serum to an antigen present in cultured burkitt's lymphoma cells.

Authors:  L J Old; E A Boyse; H F Oettgen; E D Harven; G Geering; B Williamson; P Clifford
Journal:  Proc Natl Acad Sci U S A       Date:  1966-12       Impact factor: 11.205

4.  Effect of the host cell on the maintenance and replication of Epstein-Barr virus.

Authors:  R Glaser; R Farrugia; N Brown
Journal:  Virology       Date:  1976-01       Impact factor: 3.616

5.  Cell surface markers on epithelial-Burkitt hybrid cells superinfected with Epstein-Barr virus.

Authors:  R Glaser; G Lenoir; S Ferrone; M A Pellegrino; G de-Thé
Journal:  Cancer Res       Date:  1977-07       Impact factor: 12.701

6.  Immunofluorescence in cells derived from Burkitt's lymphoma.

Authors:  G Henle; W Henle
Journal:  J Bacteriol       Date:  1966-03       Impact factor: 3.490

7.  Cellular localization of an Epstein-Barr virus (EBV)-associated complement-fixing antigen in producer and non-producer lymphoblastoid cell lines.

Authors:  B M Reedman; G Klein
Journal:  Int J Cancer       Date:  1973-05       Impact factor: 7.396

8.  Synthesis of Epstein-Barr virus antigens and DNA in activated Burkitt somatic cell hybrids.

Authors:  R Glaser; M Nonoyama; B Decker; F Rapp
Journal:  Virology       Date:  1973-09       Impact factor: 3.616

9.  Rescue of Epstein-Barr virus from somatic cell hybrids of Burkitt lymphoblastoid cells.

Authors:  R Glaser; F Rapp
Journal:  J Virol       Date:  1972-08       Impact factor: 5.103

10.  Comparison of the yield of infectious virus from clones of human and simian lymphoblastoid lines transformed by Epstein-Barr virus.

Authors:  G Miller; M Lipman
Journal:  J Exp Med       Date:  1973-12-01       Impact factor: 14.307
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  7 in total

1.  Epstein-Barr virus infection of epithelial cells derived from primary cultures of adenoidal tissue.

Authors:  M Furukawa; H Sakashita; C Kato; R Umeda
Journal:  Eur Arch Otorhinolaryngol       Date:  1990       Impact factor: 2.503

Review 2.  Does neoplasia in-situ develop due to the interaction of Epstein-Barr virus or herpes simplex virus-2 with Langerhans cells in the epithelium?

Authors:  Y Becker
Journal:  Virus Genes       Date:  1988-07       Impact factor: 2.332

3.  Expression in COS-1 cells of Epstein-Barr virus nuclear antigen from a complete gene and a deleted gene.

Authors:  M F Robert; D Shedd; R J Weigel; D K Fischer; G Miller
Journal:  J Virol       Date:  1984-06       Impact factor: 5.103

4.  Rescue of transforming Epstein-Barr virus (EBV) from EBV-genome-positive epithelial hybrid cells transfected with subgenomic fragments of EBV DNA.

Authors:  J Stoerker; R Glaser
Journal:  Proc Natl Acad Sci U S A       Date:  1983-03       Impact factor: 11.205

5.  Expression of a nuclear and a cytoplasmic Epstein-Barr virus early antigen after DNA transfer: cooperation of two distant parts of the genome for expression of the cytoplasmic antigen.

Authors:  K Takaki; A Polack; G W Bornkamm
Journal:  Proc Natl Acad Sci U S A       Date:  1984-07       Impact factor: 11.205

6.  Stable expression in mouse cells of nuclear neoantigen after transfer of a 3.4-megadalton cloned fragment of Epstein-Barr virus DNA.

Authors:  W P Summers; E A Grogan; D Shedd; M Robert; C R Liu; G Miller
Journal:  Proc Natl Acad Sci U S A       Date:  1982-09       Impact factor: 11.205

7.  Expression of Epstein-Barr virus (EBV) DNA and cloned DNA fragments in human lymphocytes following Sendai virus envelope-mediated gene transfer.

Authors:  D J Volsky; T Gross; F Sinangil; C Kuszynski; R Bartzatt; T Dambaugh; E Kieff
Journal:  Proc Natl Acad Sci U S A       Date:  1984-10       Impact factor: 11.205
  7 in total

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