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Literature DB >> 62715

The physiochemical and immunological characterization of Gm (1) antibodies from normal human serum.

Abstract

The mol. wt and charge characteristics of Gm(1) antibodies from normal human serum were studied by gel filtration and DEAE- anion exchange chromatography. The effect on anti-Gm(1) activity, of incubating individual antisera with disulphide reducing agents, and with anti-IgG or anti-IgM immunoabsorbents were also studied. The results demonstrate the existence of a low molecular weight IgM protein with anti-Gm(1) activity.

Entities: Chemical Species

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Year: 1976 PMID： 62715 PMCID： PMC1445148

Source DB: PubMed Journal: Immunology ISSN： 0019-2805 Impact factor: 7.397

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References

13 in total

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Authors: C ROPARTZ; J LENOIR; Y HEMET; L RIVAT
Journal: Nature Date: 1960-12-24 Impact factor: 49.962

2. A new type in the Gm system.

Authors: M HARBOE; J LUNDEVALL
Journal: Acta Pathol Microbiol Scand Date: 1959

3. [The human antiglobulins present in the serums of normal subjects. II. Frequency and serologic characteristics].

Authors: C ROPARTZ; J LENOIR
Journal: Rev Hematol Date: 1960 Jan-Mar

4. Dissociation of human serum macroglobulins.

Authors: H F DEUTSCH; J I MORTON
Journal: Science Date: 1957-03-29 Impact factor: 47.728

5. Agglutination of erythrocytes coated with incomplete anti-Rh by certain rheumatoid arthritic sera and some other sera; the existence of human serum groups.

Authors: R GRUBB
Journal: Acta Pathol Microbiol Scand Date: 1956

The physiochemical and immunological characterization of Gm (1) antibodies from normal human serum.

1. Possible origins of the anti-Gm sera.

2. A new type in the Gm system.

3. [The human antiglobulins present in the serums of normal subjects. II. Frequency and serologic characteristics].

4. Dissociation of human serum macroglobulins.

5. Agglutination of erythrocytes coated with incomplete anti-Rh by certain rheumatoid arthritic sera and some other sera; the existence of human serum groups.

6. Molecular heterogeneity of immunoglobulin-M (gammaM-globulin).

Review 7. Structure and function of gamma M macroglobulins.

8. Occurrence, isolation and interchain bridges of natural 7-S immunoglobulin M in human serum.

9. A Low Molecular Weight Immunoglobulin Antigenically Related to 19 S IgM.

10. Hereditary globulin factors and immune tolerance in man.