Literature DB >> 6271340

Chloride-dependent stimulation of GABA and benzodiazepine receptor binding by pentobarbital.

T Asano, N Ogasawara.   

Abstract

Pentobarbital reversibly increased Na+-dependent GABA binding to bovine cerebral cortex membranes. This effect was chloride-dependent. Kinetic analysis of [3H]GABA binding revealed an increase of the apparent number of binding sites. Pretreatment of the membranes with Triton X-100 extremely diminished the effect of pentobarbital on both [3H]GABA and [3H]flunitrazepam binding.

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Year:  1981        PMID： 6271340     DOI： 10.1016/0006-8993(81)90333-4

Source DB:  PubMed          Journal:  Brain Res        ISSN： 0006-8993            Impact factor:   3.252


  9 in total

1.  Honokiol and magnolol increase the number of [3H] muscimol binding sites three-fold in rat forebrain membranes in vitro using a filtration assay, by allosterically increasing the affinities of low-affinity sites.

Authors:  R F Squires; J Ai; M R Witt; P Kahnberg; E Saederup; O Sterner; M Nielsen
Journal:  Neurochem Res       Date:  1999-12       Impact factor: 3.996

2.  Optimal dose of thiamylal in combination with midazolam for induction of anaesthesia.

Authors:  T Nishiyama; K Hanaoka
Journal:  Can J Anaesth       Date:  1996-11       Impact factor: 5.063

3.  Additivities of compounds that increase the numbers of high affinity [3H]muscimol binding sites by different amounts define more than 9 GABA(A) receptor complexes in rat forebrain: implications for schizophrenia and clozapine research.

Authors:  R F Squires; E Saederup
Journal:  Neurochem Res       Date:  2000-12       Impact factor: 3.996

Review 4.  Biochemical dissection of the gamma-aminobutyrate synapse.

Authors:  A J Turner; S R Whittle
Journal:  Biochem J       Date:  1983-01-01       Impact factor: 3.857

5.  Actions of pentobarbitone and derivatives with modified 5-butyl substituents on GABA and diazepam binding to rat brain synaptosomal membranes.

Authors:  J H Skerritt; G A Johnston; T Katsikas; J Tabar; G M Nicholson; P R Andrews
Journal:  Neurochem Res       Date:  1983-10       Impact factor: 3.996

6.  Inhibitory effect of cephalosporins on gamma-aminobutyric acid receptor binding in rat synaptic membranes.

Authors:  S Hori; S Kurioka; M Matsuda; J Shimada
Journal:  Antimicrob Agents Chemother       Date:  1985-04       Impact factor: 5.191

7.  The gamma-aminobutyrate/benzodiazepine receptor from pig brain. Enhancement of gamma-aminobutyrate-receptor binding by the anaesthetic propanidid.

Authors:  E F Kirkness; A J Turner
Journal:  Biochem J       Date:  1986-01-01       Impact factor: 3.857

8.  Exposure to intermittent nociceptive stimulation under pentobarbital anesthesia disrupts spinal cord function in rats.

Authors:  Stephanie N Washburn; Brianne C Patton; Adam R Ferguson; Kara L Hudson; James W Grau
Journal:  Psychopharmacology (Berl)       Date:  2007-02-13       Impact factor: 4.530

9.  Effects of chronic melatonin administration on GABA and diazepam binding in rat brain.

Authors:  L P Niles; D S Pickering; M A Arciszewski
Journal:  J Neural Transm       Date:  1987       Impact factor: 3.575
  9 in total

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