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Literature DB >> 6270282

Studies on erythrocyte membranes of patients with Huntington's disease.

T M Dubbelman, A W de Bruijne, J Van Steveninck, G W Bruyn.

Abstract

Several red cell membrane properties and activities of membrane-bound enzymes were investigated in blood samples of patients with Huntington's disease. (Na(+)+K(+)) ATPase activity and cell deformability appeared to be normal, in contradiction to preceding reports from other laboratories. With other techniques sensitive to relatively small changes in membrane structure, no abnormalities were found in Huntington's disease red cell membranes. These investigations do not support the concept that a generalised membrane abnormality is present in Huntington's disease.

Entities: Disease Gene Species

Mesh：

Substances：

Year: 1981 PMID： 6270282 PMCID： PMC491060 DOI： 10.1136/jnnp.44.7.570

Source DB: PubMed Journal: J Neurol Neurosurg Psychiatry ISSN： 0022-3050 Impact factor: 10.154

21 in total

1. Release and uptake of haemoglobin and ions in red blood cells induced by dielectric breakdown.

Authors: F Riemann; U Zimmermann; G Pilwat
Journal: Biochim Biophys Acta Date: 1975-07-03

2. Fluorescence spectroscopy on Huntington's fibroblasts.

Authors: J W Pettegrew; J S Nichols; R M Stewart
Journal: J Neurochem Date: 1979-10 Impact factor: 5.372

3. Qualitative and quantitative study of the growth and cell surface properties of Huntington's disease fibroblasts and age-matched controls. Lack of significant differences.

Authors: J J Cassiman; J Verlinden; R F Vlietinck; J Bellemans; F Van Leuven; J Deroover; F Baro; H Van den Berghe
Journal: Hum Genet Date: 1979 Impact factor: 4.132

4. Electron spin resonance, hematological, and deformability studies of erythrocytes from patients with Huntington's disease.

Authors: D A Butterfield; M J Purdy; W R Markesbery
Journal: Biochim Biophys Acta Date: 1979-03-08

5. Electrophoretic analysis of the major polypeptides of the human erythrocyte membrane.

Authors: G Fairbanks; T L Steck; D F Wallach
Journal: Biochemistry Date: 1971-06-22 Impact factor: 3.162

6. Role of geometry, of size and shape, in the microcirculation.

Authors: A C Burton
Journal: Fed Proc Date: 1966 Nov-Dec

7. Selective association of spectrin with the cytoplasmic surface of human erythrocyte plasma membranes. Quantitative determination with purified (32P)spectrin.

Authors: V Bennett; D Branton
Journal: J Biol Chem Date: 1977-04-25 Impact factor: 5.157

Studies on erythrocyte membranes of patients with Huntington's disease.

1. Release and uptake of haemoglobin and ions in red blood cells induced by dielectric breakdown.

2. Fluorescence spectroscopy on Huntington's fibroblasts.

3. Qualitative and quantitative study of the growth and cell surface properties of Huntington's disease fibroblasts and age-matched controls. Lack of significant differences.

4. Electron spin resonance, hematological, and deformability studies of erythrocytes from patients with Huntington's disease.

5. Electrophoretic analysis of the major polypeptides of the human erythrocyte membrane.

6. Role of geometry, of size and shape, in the microcirculation.

7. Selective association of spectrin with the cytoplasmic surface of human erythrocyte plasma membranes. Quantitative determination with purified (32P)spectrin.

8. Lipid fluidity and membrane protein monitoring using 1,6-diphenyl-1,3,5-hexatriene.

9. Anomalous cellular proliferation in vitro associated with Huntington's disease.

10. Membrane associated proteins and malignancy: an experimental hypothesis.

1. Electron spin resonance of erythrocytes in Huntington's disease.

Review 2. The current state of research with peripheral tissues in Huntington disease.