Literature DB >> 6269058

The nucleotide sequence of rat alpha-tubulin: 3'-end characteristics, and evolutionary conservation.

I Ginzburg, L Behar, D Givol, U Z Littauer.   

Abstract

The structure and sequence of rat alpha-tubulin cDNA clone is being described. The 3'-end of the coding region contains the codon for a C-terminal tyrosine, which was previously considered to be post-translationally added to the completed polypeptide chain. A close homology in the coding sequence is observed when a-tubulin from rat and chick are compared, while the 3-non-translated region had diverged considerably.

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Year:  1981        PMID: 6269058      PMCID: PMC326885          DOI: 10.1093/nar/9.12.2691

Source DB:  PubMed          Journal:  Nucleic Acids Res        ISSN: 0305-1048            Impact factor:   16.971


  15 in total

1.  An enzyme tyrosylating alpha-tubulin and its role in microtubule assembly.

Authors:  D Raybin; M Flavin
Journal:  Biochem Biophys Res Commun       Date:  1975-08-04       Impact factor: 3.575

2.  A new method for sequencing DNA.

Authors:  A M Maxam; W Gilbert
Journal:  Proc Natl Acad Sci U S A       Date:  1977-02       Impact factor: 11.205

3.  Purification and mapping of specific mRNAs by hybridization-selection and cell-free translation.

Authors:  R P Ricciardi; J S Miller; B E Roberts
Journal:  Proc Natl Acad Sci U S A       Date:  1979-10       Impact factor: 11.205

4.  The alpha-subunit of tubulin is preferentially associated with brain presynaptic membrnae.

Authors:  I Gozes; U Z Littauer
Journal:  FEBS Lett       Date:  1979-03-01       Impact factor: 4.124

5.  Carboxy-terminal amino acid sequence of alpha-tubulin from porcine brain.

Authors:  H Ponstingl; M Little; E Krauhs; T Kempf
Journal:  Nature       Date:  1979-11-22       Impact factor: 49.962

6.  Tubulin microheterogeneity increases with rat brain maturation.

Authors:  I Gozes; U Z Littauer
Journal:  Nature       Date:  1978-11-23       Impact factor: 49.962

7.  Coding potential and regulatory signals of the polyoma virus genome.

Authors:  E Soeda; J R Arrand; N Smolar; J E Walsh; B E Griffin
Journal:  Nature       Date:  1980-01-31       Impact factor: 49.962

8.  Purification and characterization of tubulin-tyrosine ligase from porcine brain.

Authors:  H Murofushi
Journal:  J Biochem       Date:  1980-03       Impact factor: 3.387

9.  Structure of the constant and 3' untranslated regions of the murine gamma 2b heavy chain messenger RNA.

Authors:  P W Tucker; K B Marcu; J L Slightom; F R Blattner
Journal:  Science       Date:  1979-12-14       Impact factor: 47.728

10.  Virus-specific proteins in the plasma membrane of cells lytically infected or transformed by pol-oma virus.

Authors:  Y Ito; J R Brocklehurst; R Dulbecco
Journal:  Proc Natl Acad Sci U S A       Date:  1977-10       Impact factor: 11.205

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  27 in total

1.  Both alpha-tubulin genes are transcriptionally active in Stylonychia lemnae.

Authors:  E Helftenbein; E Müller
Journal:  Curr Genet       Date:  1988-05       Impact factor: 3.886

2.  Nucleotide sequence of a macronuclear DNA molecule coding for alpha-tubulin from the ciliate Stylonychia lemnae. Special codon usage: TAA is not a translation termination codon.

Authors:  E Helftenbein
Journal:  Nucleic Acids Res       Date:  1985-01-25       Impact factor: 16.971

3.  Nucleic acid composition, codon usage, and the rate of synonymous substitution in protein-coding genes.

Authors:  A Ticher; D Graur
Journal:  J Mol Evol       Date:  1989-04       Impact factor: 2.395

4.  Common and distinct tubulin binding sites for microtubule-associated proteins.

Authors:  U Z Littauer; D Giveon; M Thierauf; I Ginzburg; H Ponstingl
Journal:  Proc Natl Acad Sci U S A       Date:  1986-10       Impact factor: 11.205

5.  Complete sequence of three alpha-tubulin cDNAs in Chinese hamster ovary cells: each encodes a distinct alpha-tubulin isoprotein.

Authors:  E M Elliott; G Henderson; F Sarangi; V Ling
Journal:  Mol Cell Biol       Date:  1986-03       Impact factor: 4.272

6.  Expression and developmental regulation of two unique mRNAs specific to brain membrane-bound polyribosomes.

Authors:  C Hall; C M Lowndes; T K Leung; D N Cooper; A M Goate; L Lim
Journal:  Biochem J       Date:  1987-06-01       Impact factor: 3.857

7.  Differential expression of three alpha-tubulin genes in Chinese hamster ovary cells.

Authors:  E M Elliott; H Okayama; F Sarangi; G Henderson; V Ling
Journal:  Mol Cell Biol       Date:  1985-01       Impact factor: 4.272

8.  Expression of human alpha-tubulin genes: interspecies conservation of 3' untranslated regions.

Authors:  N J Cowan; P R Dobner; E V Fuchs; D W Cleveland
Journal:  Mol Cell Biol       Date:  1983-10       Impact factor: 4.272

9.  Differential expression of two neural cell-specific beta-tubulin mRNAs during rat brain development.

Authors:  J F Bond; G S Robinson; S R Farmer
Journal:  Mol Cell Biol       Date:  1984-07       Impact factor: 4.272

10.  Heterogeneity of vertebrate brain tubulins.

Authors:  D J Field; R A Collins; J C Lee
Journal:  Proc Natl Acad Sci U S A       Date:  1984-07       Impact factor: 11.205

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