Literature DB >> 6266844

Antagonism by chlornaltrexamine of some effects of delta 9-tetrahydrocannabinol in rats.

F C Tulunay, I H Ayhan, P S Portoghese, A E Takemori.   

Abstract

Chlornaltrexamine (beta-CNA) a selective, long-acting irreversible opiate antagonist inhibited the analgesia, hypothermia, hypothermia tolerance and physical dependence produced by delta 9-tetrahydrocannabinol (THC) in rats. The results suggest that there are some common features between cannabis and opiates and some actions of THC may be mediated by opioid related mechanisms in the central nervous system.

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Year:  1981        PMID： 6266844     DOI： 10.1016/0014-2999(81)90217-x

Source DB:  PubMed          Journal:  Eur J Pharmacol        ISSN： 0014-2999            Impact factor:   4.432


  9 in total

1.  Open-label pilot study of injectable naltrexone for cannabis dependence.

Authors:  Daniel P Notzon; Meredith A Kelly; C Jean Choi; Martina Pavlicova; Amy L Mahony; Daniel J Brooks; John J Mariani; Frances R Levin
Journal:  Am J Drug Alcohol Abuse       Date:  2018-02-08       Impact factor: 3.829

Review 2.  Are Alcohol Anti-relapsing and Alcohol Withdrawal Drugs Useful in Cannabinoid Users?

Authors:  Patrycja Kleczkowska; Irena Smaga; Małgorzata Filip; Magdalena Bujalska-Zadrozny
Journal:  Neurotox Res       Date:  2016-08-02       Impact factor: 3.911

3.  Possible mediation of catecholaminergic pathways in the antinociceptive effect of an extract of Cannabis sativa L.

Authors:  S Ferri; E Cavicchini; P Romualdi; E Speroni; G Murari
Journal:  Psychopharmacology (Berl)       Date:  1986       Impact factor: 4.530

Review 4.  Clinical and Preclinical Evidence for Functional Interactions of Cannabidiol and Δ9-Tetrahydrocannabinol.

Authors:  Douglas L Boggs; Jacques D Nguyen; Daralyn Morgenson; Michael A Taffe; Mohini Ranganathan
Journal:  Neuropsychopharmacology       Date:  2017-09-06       Impact factor: 7.853

5.  Cannabidiol fails to reverse hypothermia or locomotor suppression induced by Δ(9) -tetrahydrocannabinol in Sprague-Dawley rats.

Authors:  Michael A Taffe; Kevin M Creehan; Sophia A Vandewater
Journal:  Br J Pharmacol       Date:  2015-01-23       Impact factor: 8.739

6.  The effects of morphine and delta-9-tetrahydrocannabinol on motor activity in rats.

Authors:  F C Tulunay; I H Ayhan; S B Sparber
Journal:  Psychopharmacology (Berl)       Date:  1982       Impact factor: 4.530

7.  The cannabinoid receptor agonists, anandamide and WIN 55,212-2, do not directly affect mu opioid receptors expressed in Xenopus oocytes.

Authors:  George R Kracke; Sean P Stoneking; Joshua M Ball; Brandon M Tilghman; Carmen C Washington; Katherine A Hotaling; Joel O Johnson; Joseph D Tobias
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  2007-10-25       Impact factor: 3.000

Review 8.  Actions of delta-9-tetrahydrocannabinol in cannabis: relation to use, abuse, dependence.

Authors:  Ziva D Cooper; Margaret Haney
Journal:  Int Rev Psychiatry       Date:  2009-04

Review 9.  Cannabinoids Modulate Neuronal Activity and Cancer by CB1 and CB2 Receptor-Independent Mechanisms.

Authors:  Ken Soderstrom; Eman Soliman; Rukiyah Van Dross
Journal:  Front Pharmacol       Date:  2017-10-10       Impact factor: 5.810
  9 in total

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