| Literature DB >> 6266532 |
T P Coohill, M Babich, W D Taylor, W Snipes.
Abstract
The plaque development of Herpes simplex virus type 1 (HSV) is slower for viruses treated with two anti-DNA agents: ultraviolet radiation (UV) or n-acetoxy-2-acetyl-aminofluorene. For HSV treated with three antimembrane agents--butylated hydroxytoluene, acridine plus near UV radiation, or ether--the plaque development time is the same as for untreated viruses. These differences hold even for viruses that survived treatment that lowered viability below the 1% level. Gamma ray inactivation of HSV produces no change in plaque development even though this agent is believed to preferentially affect viral DNA.Entities:
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Year: 1980 PMID: 6266532 PMCID: PMC1328754 DOI: 10.1016/S0006-3495(80)85111-3
Source DB: PubMed Journal: Biophys J ISSN: 0006-3495 Impact factor: 4.033