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Literature DB >> 6265992

Sendai virus in nude and germ-free rats.

Abstract

The pathogenesis of Sendai virus infection was studied in athymic and AGUS rats. The infection was more severe in the athymic rats and caused considerable clinical disease. Virus was shown to replicate in the bronchial epithelium and persisted in athymic rats for the duration of the experiment (32 days). The characteristic changes of necrosis of the bronchial epithelium and subsequent hyperplasia also persisted in this group and was accompanied by quite extensive interstitial pneumonitis. The virus failed to evoke an antibody response in the athymic rats.

Entities: Disease Species

Mesh：

Year: 1980 PMID： 6265992 PMCID： PMC7125933

Source DB: PubMed Journal: Res Vet Sci ISSN： 0034-5288 Impact factor: 2.534

19 in total

1. Peroxidase-labeled antibody technique for rapid detection of mouse hepatitis virus in cases of natural outbreaks.

Authors: P Carthew
Journal: J Infect Dis Date: 1978-09 Impact factor: 5.226

2. Pathogenesis of Sendai virus infection in the central nervous system of mice.

Authors: K Shimokata; Y Nishiyama; Y Ito; Y Kimura; I Nagata
Journal: Infect Immun Date: 1976-05 Impact factor: 3.441

3. Studies on the immune response and pathogenesis of Sendai virus infection of mice. III. The effects of cyclophosphamide.

Authors: G Blandford
Journal: Immunology Date: 1975-05 Impact factor: 7.397

4. A naturally occurring epizootic caused by Sendai virus in breeding and aging rodent colonies. II. Infection in the rat.

Authors: J D Burek; C Zurcher; M C Van Nunen; C F Hollander
Journal: Lab Anim Sci Date: 1977-12

8. Background staining and sensitivity of the unlabelled antibody-enzyme (PAP) method. Comparison with the peroxidase labelled antibody sandwich method using formalin fixed paraffin embedded material.

Authors: J Burns
Journal: Histochemistry Date: 1975-06-05

9. Furunculosis in a mouse.

Authors: J E Bywater
Journal: Vet Rec Date: 1977-11-05 Impact factor: 2.695

10. Naturally occurring mouse hepatitis virus infection in the nude mouse.

Authors: J M Ward; M J Collins; J C Parker
Journal: Lab Anim Sci Date: 1977-06

3 in total

1. Alterations in pulmonary ultrastructure and morphometric parameters induced by parainfluenza (Sendai) virus in rats during postnatal growth.

Authors: W L Castleman
Journal: Am J Pathol Date: 1984-02 Impact factor: 4.307

2. Mycoplasma pulmonis infections cause long-lasting potentiation of neurogenic inflammation in the respiratory tract of the rat.

Authors: D M McDonald; T R Schoeb; J R Lindsey
Journal: J Clin Invest Date: 1991-03 Impact factor: 14.808

3. Changes in epithelial secretory cells and potentiation of neurogenic inflammation in the trachea of rats with respiratory tract infections.

Authors: H T Huang; A Haskell; D M McDonald
Journal: Anat Embryol (Berl) Date: 1989