Literature DB >> 6264763

The in vitro effect of ethanol on the histamine-sensitive adenylate cyclase system.

M Szücs, I Karnushina.   

Abstract

The effect of low concentrations (1-5%) of ethanol on the histamine-sensitive adenylate cyclase system was examined in guinea pig gastric mucosa and hippocampus homogenate. Ethanol in these concentrations caused a dose-dependent increase of the adenylate cyclase activity, and this effect was not inhibited by histamine antagonists. Phosphodiesterase activities were not affected by these concentrations of alcohol. Our in vitro findings agree well with the results of BUNCE and PARSONS [10].

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Year:  1981        PMID： 6264763     DOI： 10.1007/bf01991488

Source DB:  PubMed          Journal:  Agents Actions        ISSN： 0065-4299


  8 in total

1.  Histamine-sensitive adenylate cyclase in mammalian brain.

Authors:  L R Hegstrand; P D Kanof; P Greengard
Journal:  Nature       Date:  1976-03-11       Impact factor: 49.962

2.  Cyclic nucleotide phosphodiesterases of human and rat gastric mucosa.

Authors:  U Klotz; K H Antonin; P Bieck
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1977-01       Impact factor: 3.000

3.  Effects of ethanol on gastric mucosal adenosine 3', 5' monophosphate (cAMP).

Authors:  L L Tague; L L Shanbour
Journal:  Life Sci       Date:  1974-03-16       Impact factor: 5.037

4.  Stimulation of jejunal adenyl cyclase by ethanol.

Authors:  H L Greene; R H Herman; S Kraemer
Journal:  J Lab Clin Med       Date:  1971-09

5.  Multiple cyclic nucleotide phosphodiesterase activities from rat brain.

Authors:  W J Thompson; M M Appleman
Journal:  Biochemistry       Date:  1971-01-19       Impact factor: 3.162

6.  Selective activation by short chain alcohols of glucagon responsive adenyl cyclase in liver.

Authors:  R E Gorman; M W Bitensky
Journal:  Endocrinology       Date:  1970-11       Impact factor: 4.736

7.  A protein binding assay for adenosine 3':5'-cyclic monophosphate.

Authors:  A G Gilman
Journal:  Proc Natl Acad Sci U S A       Date:  1970-09       Impact factor: 11.205

8.  Ethanol-stimulated acid secretion in the isolated whole stomach of the rat.

Authors:  K T Bunce; M E Parsons
Journal:  J Pharm Pharmacol       Date:  1980-01       Impact factor: 3.765
  8 in total
  2 in total

1.  Effect of ethyl alcohol on the TSH-receptor-cyclase system in thyroid and nonthyroid tissues.

Authors:  O H Clark; P L Gerend
Journal:  World J Surg       Date:  1986-10       Impact factor: 3.352

Review 2.  Alcohol and gastric acid secretion in humans.

Authors:  S Chari; S Teyssen; M V Singer
Journal:  Gut       Date:  1993-06       Impact factor: 23.059
  2 in total

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