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Literature DB >> 6263265

Ontogenic development of alpha-adrenergic receptors and responsiveness in white adipocytes.

Abstract

The influence of age on adipocyte alpha-adrenergic receptors was studied by using the binding of [3H]dihydroergocryptine to crude adipocyte membranes from hamsters of different ages (1-10 months). The number of alpha-receptor sites was found to increase with increasing age, but in contrast, their binding affinity remained unchanged. These changes in receptor concentrations, which were not related to cell-size differences, were also accompanied by parallel variations of the alpha-adrenergic responsiveness of the fat-cells.

Entities: Chemical

Mesh：

Substances：

Year: 1980 PMID： 6263265 PMCID： PMC1162422 DOI： 10.1042/bj1920947

Source DB: PubMed Journal: Biochem J ISSN： 0264-6021 Impact factor: 3.857

21 in total

1. A simple and sensitive saturation assay method for the measurement of adenosine 3':5'-cyclic monophosphate.

Authors: B L Brown; J D Albano; R P Ekins; A M Sgherzi
Journal: Biochem J Date: 1971-02 Impact factor: 3.857

2. Adrenergic receptors and cyclic AMP in the regulation of human adipose tissue lipolysis.

Authors: T W Burns; P E Langley; G A Robison
Journal: Ann N Y Acad Sci Date: 1971-12-30 Impact factor: 5.691

3. Effect of age on norepinephrine-, ACTH-, theophylline- and dibutryl cyclic AMP-induced lipolysis in isolated rat fat cells.

Authors: J Nakano; A C Gin; T Ishii
Journal: J Gerontol Date: 1971-01

4. Effect of cell size on epinephrine- and ACTH-induced fatty acid release from isolated fat cells.

Authors: O Zinder; B Shapiro
Journal: J Lipid Res Date: 1971-01 Impact factor: 5.922

5. Preparation and properties of plasma membrane and endoplasmic reticulum fragments from isolated rat fat cells.

Authors: J Avruch; D F Wallach
Journal: Biochim Biophys Acta Date: 1971-04-13

6. Lipolysis and lipogenesis from glucose in human fat cells of different sizes. Effects of insulin, epinephrine, and theophylline.

Authors: R B Goldrick; G M McLoughlin
Journal: J Clin Invest Date: 1970-06 Impact factor: 14.808

Ontogenic development of alpha-adrenergic receptors and responsiveness in white adipocytes.

1. A simple and sensitive saturation assay method for the measurement of adenosine 3':5'-cyclic monophosphate.

2. Adrenergic receptors and cyclic AMP in the regulation of human adipose tissue lipolysis.

3. Effect of age on norepinephrine-, ACTH-, theophylline- and dibutryl cyclic AMP-induced lipolysis in isolated rat fat cells.

4. Effect of cell size on epinephrine- and ACTH-induced fatty acid release from isolated fat cells.

5. Preparation and properties of plasma membrane and endoplasmic reticulum fragments from isolated rat fat cells.

6. Lipolysis and lipogenesis from glucose in human fat cells of different sizes. Effects of insulin, epinephrine, and theophylline.

7. Control of cyclic AMP levels in isolated fat cells from hamsters.

Review 8. Biochemical aspects of drug and hormone action on adipose tissue.

9. Free triiodothyronine (t3)- and thyroxine (t4) serum levels in old age.

10. Studies of glucagon resistance in large rat adipocytes: 125I-labeled glucagon binding and lipolytic capacity.

1. Evidence of functional alpha 2-adrenergic receptors in adult-rat adipocytes by using the agonist UK 14304.

2. Modulation of glucose transport in hamster adipocytes by insulin and by beta- and alpha 2-adrenoceptor agonists.