| Literature DB >> 6262453 |
J A Copeland, J Skelly, G F Mann, C R Howard, A J Zuckerman.
Abstract
The dynamics of hepatitis B surface antigen production of PLC/PRF/5 hepatoma cells were studied using a quantitative radioimmunoassay method. Maximum rates of antigen production were found in nutrient-depleted, non-dividing cultures and were temporally related to cytological changes preceding cell death. These results indicate that antigen production may be cell-cycle related and represent a terminal event.Entities:
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Year: 1980 PMID： 6262453 DOI： 10.1002/jmv.1890050310
Source DB: PubMed Journal: J Med Virol ISSN： 0146-6615 Impact factor: 2.327