Literature DB >> 6261863

Unexpected antagonism in the rat vas deferens by benzomorphans which are agonists in other pharmacological tests.

M G Gillan, H W Kosterlitz, J Magnan.   

Abstract

The benzomorphans, ethylketazocine, bremazocine and MR 2034 are pure agonists in the guinea-pig ileum and mouse vas deferens but are competitive antagonists without agonist activity in the rat vas deferens.

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Year:  1981        PMID： 6261863      PMCID： PMC2071548          DOI： 10.1111/j.1476-5381.1981.tb09098.x

Source DB:  PubMed          Journal:  Br J Pharmacol        ISSN： 0007-1188            Impact factor:   8.739


  7 in total

1.  Selective receptors for beta-endorphin on the rat vas deferens.

Authors:  R Schulz; E Faase; M Wüster; A Herz
Journal:  Life Sci       Date:  1979-02-26       Impact factor: 5.037

2.  The effects of morphine and nalorphine-like drugs in the nondependent, morphine-dependent and cyclazocine-dependent chronic spinal dog.

Authors:  P E Gilbert; W R Martin
Journal:  J Pharmacol Exp Ther       Date:  1976-07       Impact factor: 4.030

3.  The effects of morphine- and nalorphine- like drugs in the nondependent and morphine-dependent chronic spinal dog.

Authors:  W R Martin; C G Eades; J A Thompson; R E Huppler; P E Gilbert
Journal:  J Pharmacol Exp Ther       Date:  1976-06       Impact factor: 4.030

4.  Assessment in the guinea-pig ileum and mouse vas deferens of benzomorphans which have strong antinociceptive activity but do not substitute for morphine in the dependent monkey.

Authors:  M Hutchinson; H W Kosterlitz; F M Leslie; A A Waterfield
Journal:  Br J Pharmacol       Date:  1975-12       Impact factor: 8.739

5.  Characterization of opioid receptors in nervous tissue.

Authors:  H W Kosterlitz; S J Paterson
Journal:  Proc R Soc Lond B Biol Sci       Date:  1980-10-29

6.  Some quantitative uses of drug antagonists.

Authors:  O ARUNLAKSHANA; H O SCHILD
Journal:  Br J Pharmacol Chemother       Date:  1959-03

7.  Rat vas deferens: a specific bioassay for endogenous opioid peptides.

Authors:  S Lemaire; J Magnan; D Regoli
Journal:  Br J Pharmacol       Date:  1978-11       Impact factor: 8.739
  7 in total
  10 in total

1.  The binding spectrum of narcotic analgesic drugs with different agonist and antagonist properties.

Authors:  J Magnan; S J Paterson; A Tavani; H W Kosterlitz
Journal:  Naunyn Schmiedebergs Arch Pharmacol       Date:  1982-06       Impact factor: 3.000

2.  Aversive properties of naloxone in non-dependent (naive) rats may involve blockade of central beta-endorphin.

Authors:  R F Mucha; M J Millan; A Herz
Journal:  Psychopharmacology (Berl)       Date:  1985       Impact factor: 4.530

3.  Pharmacological profile of various kappa-agonists at kappa-, mu- and delta-opioid receptors mediating presynaptic inhibition of neurotransmitter release in the rat brain.

Authors:  A H Mulder; D M Burger; G Wardeh; F Hogenboom; A L Frankhuyzen
Journal:  Br J Pharmacol       Date:  1991-02       Impact factor: 8.739

4.  Effects of cations on binding, in membrane suspensions, of various opioids at mu-sites of rabbit cerebellum and kappa-sites of guinea-pig cerebellum.

Authors:  H W Kosterlitz; S J Paterson; L E Robson; J R Traynor
Journal:  Br J Pharmacol       Date:  1987-06       Impact factor: 8.739

5.  Bremazocine differentially antagonizes responses to selective mu and delta opioid receptor agonists in rat hippocampus.

Authors:  T V Dunwiddie; K J Johnson; W R Proctor
Journal:  Br J Pharmacol       Date:  1987-07       Impact factor: 8.739

6.  Bremazocine is an agonist at kappa-opioid receptors and an antagonist at mu-opioid receptors in the guinea-pig myenteric plexus.

Authors:  A D Corbett; H W Kosterlitz
Journal:  Br J Pharmacol       Date:  1986-09       Impact factor: 8.739

7.  Effect of sodium on [3H]ethylketocyclazocine binding to opioid receptors in frog brain membranes.

Authors:  S Benyhe; T Farkas; M Wollemann
Journal:  Neurochem Res       Date:  1989-03       Impact factor: 3.996

8.  Postjunctional inhibition of contractor responses in the mouse vas deferens by rat and human calcitonin gene-related peptides (CGRP).

Authors:  S J Al-Kazwini; R K Craig; I Marshall
Journal:  Br J Pharmacol       Date:  1986-05       Impact factor: 8.739

9.  Pre-incubation of guinea-pig myenteric plexus with beta-funaltrexamine: discrepancy between binding assays and bioassays.

Authors:  A D Corbett; H W Kostelitz; A T McKnight; S J Paterson; L E Robson
Journal:  Br J Pharmacol       Date:  1985-07       Impact factor: 8.739

10.  Opioid effects in developing rat vas deferens.

Authors:  A Z Rónai; I P Berzétei; J Kurgyis
Journal:  Cell Mol Neurobiol       Date:  1981-12       Impact factor: 5.046
  10 in total

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