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Literature DB >> 6261328

Compartmentalization of cyclic AMP during phagocytosis by human neutrophilic granulocytes.

K B Pryzwansky, A L Steiner, J K Spitznagel, C L Kapoor.

Abstract

Immunocytochemistry shows that early during phagocytosis of zymosan, adenosine 3',5'-monophosphate (cyclic AMP) appears on the cell surface before the phagosome is internalized. The appearance of cyclic AMP on the cell surface is coincident with that of granule products and regulatory subunit of type I cyclic AMP-dependent protein kinase. Guanosine 3',5'-monophosphate is not associated with the initiation site of phagocytosis, but is observed throughout the granular cytoplasmic region. This sharply localized accumulation of cyclic AMP may serve as a signal for the initiation of phagocytosis.

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Year: 1981 PMID： 6261328 DOI： 10.1126/science.6261328

Source DB: PubMed Journal: Science ISSN： 0036-8075 Impact factor: 47.728

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Cited

13 in total

1. Ultracytochemical localization of guanylate cyclase activity in guinea-pig peritoneal macrophages under different physiological conditions.

Authors: G Dini; M Del Rosso
Journal: Histochem J Date: 1984-12

Review 2. A-kinase anchoring proteins: a key to selective activation of cAMP-responsive events?

Authors: V M Coghlan; S E Bergeson; L Langeberg; G Nilaver; J D Scott
Journal: Mol Cell Biochem Date: 1993-11 Impact factor: 3.396

3. Differences of adenylate cyclase localization in guinea-pig peritoneal macrophages under different physiological conditions: an ultracytochemical study.

Authors: G Dini; M Del Rosso
Journal: Histochem J Date: 1983-09

4. T cell receptor induced intracellular redistribution of type I protein kinase A.

Authors: Wenhong Zhou; Leoncio Vergara; Rolf König
Journal: Immunology Date: 2004-12 Impact factor: 7.397

5. Effect of endothelium on basal and on stimulated accumulation and efflux of cyclic GMP in rat isolated aorta.

Authors: V Schini; P Schoeffter; R C Miller
Journal: Br J Pharmacol Date: 1989-07 Impact factor: 8.739

6. Early changes in cyclic AMP and calcium efflux during phagocytosis by neutrophils from normals and patients with chronic granulomatous disease.

Authors: T Herlin; N Borregaard
Journal: Immunology Date: 1983-01 Impact factor: 7.397

Compartmentalization of cyclic AMP during phagocytosis by human neutrophilic granulocytes.

1. Ultracytochemical localization of guanylate cyclase activity in guinea-pig peritoneal macrophages under different physiological conditions.

Review 2. A-kinase anchoring proteins: a key to selective activation of cAMP-responsive events?

3. Differences of adenylate cyclase localization in guinea-pig peritoneal macrophages under different physiological conditions: an ultracytochemical study.

4. T cell receptor induced intracellular redistribution of type I protein kinase A.

5. Effect of endothelium on basal and on stimulated accumulation and efflux of cyclic GMP in rat isolated aorta.

6. Early changes in cyclic AMP and calcium efflux during phagocytosis by neutrophils from normals and patients with chronic granulomatous disease.

7. Phagosomal membrane lipids of LM fibroblasts.

8. Modulatory role of cyclic AMP in the release of platelet-activating factor from human polymorphonuclear leucocytes.

9. Beta-adrenoceptor-mediated modulation of calcium ionophore activated polymorphonuclear leucocytes.

10. Transient increase in cyclic AMP localized to macrophage phagosomes.