Literature DB >> 7935359

A-kinase anchoring proteins: a key to selective activation of cAMP-responsive events?

V M Coghlan1, S E Bergeson, L Langeberg, G Nilaver, J D Scott.   

Abstract

The cAMP-dependent protein kinase (PKA) regulates a variety of diverse biochemical events through the phosphorylation of target proteins. Because PKA is a multifunctional enzyme with a broad substrate specificity, its compartmentalization may be a key regulatory event in controlling which particular target substrates are phosphorylated. In recent years it has been demonstrated that differential localization of the type II holoenzyme is directed through interaction of the regulatory subunit (RII) with a family of A-Kinase Anchoring Proteins (AKAPs). In this report, we review evidence for PKA compartmentalization and discuss the structural and functional properties of AKAPs.

Entities:  

Mesh：

Substances：

Year:  1993        PMID： 7935359     DOI： 10.1007/978-1-4615-2600-1_28

Source DB:  PubMed          Journal:  Mol Cell Biochem        ISSN： 0300-8177            Impact factor:   3.396


  96 in total

Review 1.  Blotting and band-shifting: techniques for studying protein-protein interactions.

Authors:  D W Carr; J D Scott
Journal:  Trends Biochem Sci       Date:  1992-07       Impact factor: 13.807

2.  Characterization and comparison of membrane-associated and cytosolic cAMP-dependent protein kinases. Physicochemical and immunological studies on bovine cerebral cortex protein kinases.

Authors:  C S Rubin; R Rangel-Aldao; D Sarkar; J Erlichman; N Fleischer
Journal:  J Biol Chem       Date:  1979-05-25       Impact factor: 5.157

3.  Ultrastructural localization of cAMP-dependent protein kinase subunits in regenerating rat hepatocytes using immunogold electron microscopy.

Authors:  S P Squinto; D C Kelley-Geraghty; M R Kuettel; R A Jungmann
Journal:  J Cyclic Nucleotide Protein Phosphor Res       Date:  1985

4.  A cloned bovine cDNA encodes an alternate form of the catalytic subunit of cAMP-dependent protein kinase.

Authors:  M O Showers; R A Maurer
Journal:  J Biol Chem       Date:  1986-12-15       Impact factor: 5.157

Review 5.  Role of protein phosphorylation in neuronal signal transduction.

Authors:  H C Hemmings; A C Nairn; T L McGuinness; R L Huganir; P Greengard
Journal:  FASEB J       Date:  1989-03       Impact factor: 5.191

6.  Evidence for a second isoform of the catalytic subunit of cAMP-dependent protein kinase.

Authors:  M D Uhler; J C Chrivia; G S McKnight
Journal:  J Biol Chem       Date:  1986-11-25       Impact factor: 5.157

7.  Regulation of kainate receptors by cAMP-dependent protein kinase and phosphatases.

Authors:  L Y Wang; M W Salter; J F MacDonald
Journal:  Science       Date:  1991-09-06       Impact factor: 47.728

8.  Isolation of a cDNA clone for the type I regulatory subunit of bovine cAMP-dependent protein kinase.

Authors:  D C Lee; D F Carmichael; E G Krebs; G S McKnight
Journal:  Proc Natl Acad Sci U S A       Date:  1983-06       Impact factor: 11.205

9.  Mechanism of self-phosphorylation of adenosine 3':5'-monophosphate-dependent protein kinase from bovine cardiac muscle.

Authors:  R Rangel-Aldao; O M Rosen
Journal:  J Biol Chem       Date:  1976-12-10       Impact factor: 5.157

10.  Myristoyl CoA:protein N-myristoyltransferase activities from rat liver and yeast possess overlapping yet distinct peptide substrate specificities.

Authors:  D A Towler; S P Adams; S R Eubanks; D S Towery; E Jackson-Machelski; L Glaser; J I Gordon
Journal:  J Biol Chem       Date:  1988-02-05       Impact factor: 5.157
View more
  9 in total

1.  Cloning and mitochondrial localization of full-length D-AKAP2, a protein kinase A anchoring protein.

Authors:  L Wang; R K Sunahara; A Krumins; G Perkins; M L Crochiere; M Mackey; S Bell; M H Ellisman; S S Taylor
Journal:  Proc Natl Acad Sci U S A       Date:  2001-03-13       Impact factor: 11.205

Review 2.  Structure-function of the multifunctional Ca2+/calmodulin-dependent protein kinase II.

Authors:  Andy Hudmon; Howard Schulman
Journal:  Biochem J       Date:  2002-06-15       Impact factor: 3.857

3.  Action of rolipram on specific PDE4 cAMP phosphodiesterase isoforms and on the phosphorylation of cAMP-response-element-binding protein (CREB) and p38 mitogen-activated protein (MAP) kinase in U937 monocytic cells.

Authors:  S J MacKenzie; M D Houslay
Journal:  Biochem J       Date:  2000-04-15       Impact factor: 3.857

4.  An autoregulatory region in protein kinase C: the pseudoanchoring site.

Authors:  D Ron; D Mochly-Rosen
Journal:  Proc Natl Acad Sci U S A       Date:  1995-01-17       Impact factor: 11.205

Review 5.  Biological significance of phosphorylation and myristoylation in the regulation of cardiac muscle proteins.

Authors:  R V Raju; R Kakkar; J M Radhi; R K Sharma
Journal:  Mol Cell Biochem       Date:  1997-11       Impact factor: 3.396

6.  In vitro phosphorylation of bovine cardiac muscle high molecular weight calmodulin binding protein by cyclic AMP-dependent protein kinase and dephosphorylation by calmodulin-dependent phosphatase.

Authors:  R Kakkar; S Taketa; R V Raju; S Proudlove; P Colquhoun; K Grymaloski; R K Sharma
Journal:  Mol Cell Biochem       Date:  1997-12       Impact factor: 3.396

7.  cAMP-dependent protein kinase phosphorylations on tau in Alzheimer's disease.

Authors:  G A Jicha; C Weaver; E Lane; C Vianna; Y Kress; J Rockwood; P Davies
Journal:  J Neurosci       Date:  1999-09-01       Impact factor: 6.167

8.  Protein kinase A-dependent step(s) in hepatitis C virus entry and infectivity.

Authors:  Michelle J Farquhar; Helen J Harris; Mandy Diskar; Sarah Jones; Christopher J Mee; Søren U Nielsen; Claire L Brimacombe; Sonia Molina; Geoffrey L Toms; Patrick Maurel; John Howl; Friedrich W Herberg; Sven C D van Ijzendoorn; Peter Balfe; Jane A McKeating
Journal:  J Virol       Date:  2008-06-25       Impact factor: 5.103

9.  Isolation of novel differentially expressed genes related to human glioma using cDNA microarray and characterizations of two novel full-length genes.

Authors:  Zhen-Yu Qi; Yao Li; Kang Ying; Chao-Qun Wu; Rong Tang; Zong-Xiang Zhou; Zhong-Ping Chen; Guo-Zhen Hui; Yi Xie
Journal:  J Neurooncol       Date:  2002-02       Impact factor: 4.130
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.