| Literature DB >> 6259539 |
Abstract
The SV40 early region TATA box functions in vitro to fix initiation of transcription within a narrow region identical to that in vivo. In the absence of the TATA box region initiation occurs at multiple specific sites, as in vivo. However, certain sequences far upstream, crucial for efficient in vivo expression, are not essential in vitro.Mesh:
Substances:
Year: 1981 PMID: 6259539 DOI: 10.1038/290310a0
Source DB: PubMed Journal: Nature ISSN: 0028-0836 Impact factor: 49.962